Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 684-597-9 | CAS number: 1072005-10-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
No data on the test item is available. With the read-across substances the following results were obtained:
Fish:
CAS 68583-51-7: EC50 > 39 mg/L, NOEC = 39 mg/L
CAS 853947-59-8: EC50 > 14 mg/L, NOEC = 14 mg/L
Daphnia:
CAS 68583-51-7: EC50 >2.7 mg/L, NOEC = 2.7 mg/L
CAS 853947-59-8: EC50 >2.0 mg/L, NOEC = 2.0 mg/L
Algae:
CAS 68583-51-7: EC50 >5.3 mg/L, EC10 >5.3 mg/L, NOEC ≥ 5.3 mg/L
CAS 853947-59-8: EC50 >3.0 mg/L, EC10 >3.0 mg/L, NOEC ≥ 3.0 mg/L
Microorganisms:
CAS 68583-51-7: EC10 > 0.9 g/L, NOEC = 0.9 g/L
CAS 853947-59-8: EC10 > 1.1 g/L, NOEC = 1.1 g/L
Additional information
No data on the test item is available. With the read-across substances the following results were obtained:
Fish:
The toxicity of the read-across substance CAS 68583-51-7 to fish (Danio rerio) was determined according to the principles of OECD 203. The aim of the study was the determination of NOEC, LOEC, EC10- , EC20- and EC50-values of lethality over a period of 96 hours. The study was conducted under semi-static conditions with renewal of the test solution after 24 h. A stock solution of 1 g/L was prepared with deionised water. The concentration was calculated from the new solutions to be 39 mg/L. Two replicates were tested for the test item concentration and for the control. The environmental conditions were within the acceptable limits. No lethality was observed. The following results were determined: EC50 >39 mg/L, NOEC = 39 mg/L, LOEC > 39 mg/L.
The toxicity of the read-across substance CAS 853947-59-8 to fish (Cyprinus carpio) was determined according to the principles of OECD 203. The aim of the study was the determination of NOEC, LOEC, EC10- , EC20- and EC50-values of lethality over a period of 96 hours. The study was conducted under semi-static conditions with renewal of the test solution after 24 h. A stock solution of 1 g/L was prepared with deionised water. The concentration was calculated from the new solutions to be 14 mg/L. Two replicates were tested for the test item concentration and for the control. The environmental conditions were within the acceptable limits. No lethality was observed. The following results were determined: EC50 >14 mg/L, NOEC = 14 mg/L, LOEC > 14 mg/L.
Daphnia:
The toxicity of the read-across substance CAS 68583-51-7 to Daphnia magna was determined according to the principles of OECD 202. The aim of the study was the determination of NOEC, LOEC, EC10- , EC20- and EC50-values of immobilsation over a period of 48 hours. The study was conducted under static conditions. A stock solution of 1 g/L was prepared with deionised water. One concentration was tested: 2.7 mg/L. Five replicates were tested for the test item concentration and for the control. The environmental conditions were within the acceptable limits. The concentrations of the test item in the test concentration and the control were analytically verified by TOC Infrared analyser at the start and the end of exposure. The measured concentrations were in the range of 20 % of the nominal value. Therefore, all effect values given are based on the nominal test item concentrations. No immobilistion was observed. The following results were determined: EC50 >2.7 mg/L, NOEC = 2.7 mg/L, LOEC > 2.7 mg/L.
The toxicity of the read-across substance 853947-59-8 to Daphnia magna was determined according to the principles of OECD 202. The aim of the study was the determination of NOEC, LOEC, EC10- , EC20- and EC50-values of immobilsation over a period of 48 hours. The study was conducted under static conditions. A stock solution of 1 g/L was prepared with deionised water. One concentration was tested: 2.0 mg/L. Five replicates were tested for the test item concentration and for the control. The environmental conditions were within the acceptable limits. The analytical determination of the stability of the test item was tested separately. Concentrations of 0.5, 1.2 and 2.4 mg/L were analyzed after 24, 48 and 72 h. The recovery rate was >80%, therefor nominal values were used for the test. During the test no concentrations were measured. No immobilistion was observed. The following results were determined: EC50 >2.0 mg/L, NOEC = 2.0 mg/L, LOEC > 2.0 mg/L.
Algae:
The toxicity of the read across substance CAS 68583-51-7 to the unicellular freshwater green alga Desmodesmus subspicatus was determined according to the principles of OECD 201. The aim of the study was the determination of NOEC, LOEC, EC10- , EC20- and EC50-values of growth rate and yield over a period of 72 hours. The study was conducted under static conditions with an initial cell density of 20.000 cells/mL. A stock solution of 1 g/L was prepared with deionised water. Five concentrations were tested in a geometrical series (nominal): 0.59 - 0.99 - 1.8 - 2.9 - 5.3 mg/L. Five replicates were tested for each test item concentration and eight replicates for the control. The environmental conditions were within the acceptable limits. The concentrations of the test item in all test concentrations and the control were analytically verified by TOC Infrared analyser at the start and the end of exposure. The measured concentrations were in the range of 20 % of the nominal values of all concentrations. Therefore, all effect values given are based on the geometric mean measured test item concentrations. The following geometric mean measured results were determined: EC50 >5.3 mg/L, EC10 >5.3 mg/L, NOEC ≥ 5.3 mg/L.
The toxicity of the read-across substance CAS 853947-59-8 to the unicellular freshwater green alga Desmodesmus subspicatus was determined according to the principles of OECD 201. The aim of the study was the determination of NOEC, LOEC, EC10- , EC20- and EC50-values of growth rate and yield over a period of 72 hours. The study was conducted under static conditions with an initial cell density of 20.000 cells/mL. A stock solution of 1 g/L was prepared with deionised water. One concentration was tested: 3.0 mg/L. Five replicates were tested for the test item concentration and eight replicates for the control. The environmental conditions were within the acceptable limits. The analytical determination of the stability of the test item was tested separately. Concentrations of 0.5, 1.2 and 2.4 mg/L were analyzed after 24, 48 and 72 h. The recovery rate was >80%, therefor nominal values were used for the test. During the test no concentrations were measured. Therefore, all effect values given are based on the geometric mean measured test item concentrations. The following geometric mean measured results were determined: EC50 >3.0 mg/L, EC10 >3.0 mg/L, NOEC ≥ 3.0 mg/L.
Microorganisms:
In the oxygen-consumption test according to Hüls AG (Dr. Schöberl) the respiration inhibition of the read across substance CAS 68583-51-7 was determined. Four concentrations of 0.99, 9.9, 99 and 990 mg/L were used. After incubation of 4.75 h with Pseudomonas putida Migula the respiration of the organisms was stimulated and not inhibited. Therefor the EC10 and EC50 > 0.99 g/L.
In the oxygen-consumption test according to OECD 209 the respiration inhibition of the read across substance CAS 853947-59-8 was determined. The concentrations of 45.8, 91.6, 183.2, 366.4 and 1099 mg/L were used. After incubation of 3 h with activated sludge the respiration of the organisms was stimulated and not inhibited. Therefor the EC10 and EC50 > 1.1 g/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.