Registration Dossier
Registration Dossier
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EC number: 807-747-9 | CAS number: 144429-84-5
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
NOECreproduction (56d) = 250 mg/kg soil d.w.
LC50 (14d) > 1000mg/kg dw
Key value for chemical safety assessment
Additional information
Acute test towards earthworm (OECD 207) with the target substance:
The acute toxicity towards earthworm was tested in a GLP-study according to OECD guideline 207 (2018) in a 14-day limit test with the nominal concentration of 1000 mg/kg dry soil. No mortality and no other adverse effects were recorded in the test.
Chronic test towards earthworm 56d (OECD 222) with similar source substance (EC 406 -040 -9):
The chronic toxicity of the read-across substance towards earth worms was determined in a GLP test according to OECD guideline 222 using artificial soil (ECT 2006).
The NOEC for biomass (28 days) was determined to be >1000 mg test item/kg soil (dw). The 56 day NOEC for reproduction was determined as 250 mg test item/kg soil (dw) and the LOEC reproduction was determined as 500 mg test item/kg soil (dw). The EC50 value (56 days) for reproduction was calculated as 945,44 mg test item/kg soil (dw).
Acute test towards earthworm (OECD 207) with similar source substance (EC 406 -040 -9):
In addition, the acute toxicity towards earthworm was tested in a GLP-study according to OECD guideline 207 (1984) in a 14-day test with nominal concentrations of 96, 172, 309, 556, 1000 mg/kg dry soil. No significant mortality and no abnormal behavior or symptoms of toxicity were recorded at any test concentration.
It can be concluded that the substance is acutely not toxic to earthworms but shows toxic effects after chronic exposure.
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