Registration Dossier
Registration Dossier
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EC number: 295-893-9 | CAS number: 92129-93-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 998
- Report date:
- 1998
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Whey, lactose-low
- EC Number:
- 295-893-9
- EC Name:
- Whey, lactose-low
- Cas Number:
- 92129-93-6
- IUPAC Name:
- Whey, lactose-low
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Remarks:
- the samples were analysed for chlorophyll a fluorescence
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Selenastrum sp.
- Details on test organisms:
- Selenastrum capricornutum, IAER-clone
Study design
- Test type:
- not specified
- Water media type:
- not specified
- Limit test:
- no
- Total exposure duration:
- 72 h
Test conditions
- Hardness:
- not specified
- Test temperature:
- 23°C (start) - 21.5°C (end)
- pH:
- 8.1-8.4 (start) and 8.1-8.2 (end)
- Dissolved oxygen:
- not specified
- Salinity:
- not specified
- Conductivity:
- not specified
- Nominal and measured concentrations:
- 6.25, 12.5, 25, 50, 100 and 200 mg/L
- Reference substance (positive control):
- yes
- Remarks:
- potassium dichromate
Results and discussion
Effect concentrationsopen allclose all
- Key result
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 200 mg/L
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- EC10
- Effect conc.:
- > 200 mg/L
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Key result
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- > 200 mg/L
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Results with reference substance (positive control):
- The reference substance, potassium dichromate, gave an EC50 within the proposed interval (0.5-1.1) according to OECD 201.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The compound is not toxic to the green algae Selenastrum capricornutum at 200 mg/L or less.
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