Registration Dossier
Registration Dossier
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EC number: 242-833-4 | CAS number: 19139-31-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Vehicle:
- yes
- Remarks:
- DMF
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 0.027 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Key result
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.027 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Sublethal observations / clinical signs:
Analysis of the exposure solutions
Nominal Conc (mg/L)
Measured Concentration (mg/L)
Geometric Mean Measured Concentration
(mg/L)
0 hour (fresh)
24 hour (old)
72 hour (fresh)
96 hour (old)
Control
ND
ND
ND
ND
-
Solv Ctrl
ND
ND
ND
ND
-
0.010
0.0915
0.014
0.0812
0.0040
0.027
Percentage mortality and sub-lethal effects
Geometric Mean
Measured Concentration(mg/L)
1 hour
3 hours
6 hours
24 hours
48 hours
72 hours
96 hours
Control
0
0
0
0
0
0
0
Solv Ctrl
0
0
0
0
0
0
0
0.027
0
0
0
0
0
0
0
No sub-lethal effects were observed throughout the exposure period
RESULTS
96 Hour LC50
95% Confidence Limits
NOEC
LOEC
>0.027
Not determined
0.027
Not determined
- Validity criteria fulfilled:
- not specified
- Conclusions:
- After 96 hours of exposure, no effects were observed at the maximum concentration tested. The initial loading rate was 0.1 mg/L, which was the maximum test concentration possible.
Reference
Description of key information
After 96 hours of exposure, no effects were observed at the maximum concentration tested. The initial loading rate was 0.1 mg/L, which was the maximum test concentration possible.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.1 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
