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EC number: 204-729-7 | CAS number: 125-20-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- effusion method: Knudsen cell
Test material
- Reference substance name:
- 3,3-bis(4-hydroxy-5-isopropyl-o-tolyl)phthalide
- EC Number:
- 204-729-7
- EC Name:
- 3,3-bis(4-hydroxy-5-isopropyl-o-tolyl)phthalide
- Cas Number:
- 125-20-2
- Molecular formula:
- C28H30O4
- IUPAC Name:
- 3,3-bis(4-hydroxy-5-isopropyl-o-tolyl)phthalide
- Details on test material:
- - Storage conditions: Room Temperature (20 ± 5 °C)
- Expiry date: 16. Dec. 2019
Constituent 1
Results and discussion
Vapour pressure
- Temp.:
- 90 °C
- Vapour pressure:
- 0.002 Pa
- Remarks on result:
- other: Nine different temperatures were examined, but none could be evaluated (no reproducible or relevant weight loss). Calculation on base of measured weight losses is not possible, highest mean VP, derived from all measurements, is stated as limit value.
Applicant's summary and conclusion
- Conclusions:
- Vapour pressure was examined at nine different temperatures. No temperatures could be evaluated as they showed no reproducible or relevant weight loss. As a calculation on base of the measured weight losses is not possible, the highest mean vapour pressure, derived from all measurements, is stated as limit value.
Vapour pressure at 90 °C: 1.50* 10E-03Pa
The study was performed according to the OECD TG104 and EU Method A.4 without deviations and therefore considered to be of the highest quality (reliability Klimisch 1). - Executive summary:
The vapour pressure of the test item was determined in a study according to OECD 104 resp. EU Method A.4 ( effusion method: Knudsen cell).
The test substance was weighed into the Knudsen cells until the latter were 2/3 full. The Knudsen cells were closed using a crimp-cap with hole and an aluminium plate with an aperture of 1 mm diameter.
Four Knudsen cells were prepared in this way and set into the vacuum chamber. The vacuum chamber was evacuated to 10E-07 Pa or lower. Every day, vacuum was released; the Knudsen cells were taken out and weighed. After weighing, the cells were built in again and the vacuum was regenerated.
Throughout the measurement, the temperature of the vacuum chamber was held constant using an electrical heating device (± 1.0 °C).
First, the determination was performed at 30 °C. Then, further determinations were made at 45, 60 and 75 °C. Due to organisational reasons, the cells were stored in an desiccator under argon between two measurement series. The positive control was tested in the same manner.
Vapour pressure was examined at nine different temperatures. No temperatures could be evaluated as they showed no reproducible or relevant weight loss. As a calculation on base of the measured weight losses is not possible, the highest mean vapour pressure, derived from all measurements, is stated as limit value.
Vapour pressure at 90 °C: 1.50* 10E-03Pa
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