Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 268-820-3 | CAS number: 68140-98-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Version / remarks:
- Adopted: 17 July 1992
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- - Source of inoculum/activated sludge: Activated sludge from aeration tank of a well-operated wastewater treatment plant receiving predominantly domestic sewage (WWTP Spišská Nová Ves).
- Pretreatment: Sludge was collected on the day of analysis. The sludge was used as collected but coarse particles were removed by settling for a short period, ca 15 minutes, and decanting the upper layer of finer solids and it was aerated by air without CO2 (CO2 was catched in the absorption flask with 0.05 mol/L NaOH) (ca 2 L/minutes) at the test temperature until it was used in the test.
- Concentration of sludge: 3.0 g/L susp. solids
- Initial cell/biomass concentration: 30.0 mg/ L suspended solids - Duration of test (contact time):
- 28 d
- Initial conc.:
- 18 mg/L
- Based on:
- TOC
- Initial conc.:
- 24 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium: mineral medium according to Guideline
- Test temperature: 22.3 - 24.0°C
- pH: 7.64 - 8.18
SAMPLING
- Sampling frequency: Samples were collected for TIC analysis on the 1st day, 3rd, 6th, 8th, 10th, 14th, 21st, 28th, 29th day.
CONTROL AND BLANK SYSTEM
- Inoculum blank: 2 flasks
- Procedure control: 1 flask
- Abiotic sterile control: 1 flask
- Toxicity control: 1 flask - Reference substance:
- other: D+glucose (C6H12O6), 12 mg DOC/L
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 34.73
- Sampling time:
- 28 d
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- In a screening test according to OECD 301 B CO2 Evolution (Modified Sturm Test), the test item was degraded to 34.73% after 28 days.
- Executive summary:
Ready biodegradability of MC A45A was tested in a screening test according to OECD 301 B. The percentage of biodegradation was determined by measurements of CO2 evolution. Due to the limited water solubility of the test item, Tween 80 was used as emulsifier.
The results of the controls indicate that the validity criteria of the test were met.
Reference
Degradation results:
Day |
% Degradation |
1 |
0.10 |
3 |
0.77 |
6 |
2.12 |
8 |
3.26 |
10 |
5.00 |
14 |
7.81 |
21 |
13.49 |
29 |
34.73 |
Description of key information
In a screening test according to OECD 301 B MC A45A was not readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- inherently biodegradable
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.