Pyrogallol

Appearance / physical state / colour

Administrative data

Endpoint:

appearance / physical state / colour

Type of information:

other: observation

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Data source

Reference

Reference Type:

review article or handbook

Title:

Final Report on the Safety Assessment of Pyrogallol

Author:

CIR - COSMETIC INGREDIENT REVIEW

Year:

1991

Bibliographic source:

JOURNAL OF THE AMERICAN COLLEGE OF TOXICOLOGY. 10(1): 67-85

Materials and methods

Test guideline

Qualifier:

no guideline required

Principles of method if other than guideline:

- Principle of test: There is no guideline method for this endpoint. Data presented based on visual observation (supported by data on melting point)
- Short description of test conditions: an observation at standard temperature and pressure was performed.
- Parameters analysed / observed: physical state, color and odor of the substance.

GLP compliance:

not specified

Other quality assurance:

other: not specified

Remarks:

primary source: WINDHOLZ, M., BUDVARI, S., BLUMETTI, R.F., and OTTERBEIN, F.A. 119831. The Merck Index, 10th ed. Rahway, NJ: Merck and Co., Inc., p, 1154

Test material

Test material information

Constituent 1

Reference substance name:

Pyrogallol

EC Number:

201-762-9

EC Name:

Pyrogallol

Cas Number:

87-66-1

Molecular formula:

C6H6O3

IUPAC Name:

benzene-1,2,3-triol

impurity 1

Reference substance name:

unknown impurities

IUPAC Name:

unknown impurities

Test material form:

not specified

Details on test material:

not specified

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: not specified
- Expiration date of the lot/batch: not specified
- Purity test date: not specified

RADIOLABELLING INFORMATION (if applicable) not applicable
- Radiochemical purity: -
- Specific activity: -
- Locations of the label: -
- Expiration date of radiochemical substance: -

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: not specified
- Stability under test conditions: not specified
- Solubility and stability of the test substance in the solvent/vehicle: not specified
- Reactivity of the test substance with the solvent/vehicle of the cell culture medium: not specified

TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: not relevant
- Preliminary purification step (if any): not specified
- Final dilution of a dissolved solid, stock liquid or gel: not relevant
- Final preparation of a solid: not relevant

FORM AS APPLIED IN THE TEST (if different from that of starting material) solid

TYPE OF BIOCIDE/PESTICIDE FORMULATION (if applicable) not applicable

OTHER SPECIFICS: Pyrogallol consists of a minimum of 99% Pyrogallol.
A UV spectral analysis of chemically pure (99%) Pyrogallol, 0.1% w/v in methanol, showed a single absorbance maximum at 267.5 nm

Results and discussion

Physical state at 20°C and 1013 hPa:

solid

Form / colour / odour

Key result

Form:

solid: crystalline

Remarks:

(crystals)

Colour:

white

Odour:

odourless

Substance type:

organic

Applicant's summary and conclusion

Conclusions:

Pyrogallol is an organic solid and ordorless at standard temperature and pressure.

Executive summary:

Pyrogallol is an organic solid and ordorless at standard temperature and pressure (@20°C and 1013 hPa).

No information on data or the test method used to measure this endpoint are available in the handbook. However, this information is taken from a peer reviewed handbook (primary source: The Merck Index, 10th ed) and mentioned in a high quality review so, it can be considered reliable and suitable for use as the key study for this endpoint

.