[2-(2-methoxyethoxy)ethoxy]acetic acid

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

from 2017-10-02 to 2017-10-18

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7220 (Boiling Point / Boiling Range)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

method according to Siwoloboff

Specific details on test material used for the study:

Batch No.: 08/2016_R_JM
Purity: 97.5 %

Key result

Boiling pt.:

256.7 °C

Atm. press.:

99.65 kPa

Preliminary Test

Start temperature, °C	Heating rate, °C/min	Atmospheric pressure, kPa (at the measuring)	Boiling point, °C (at standard atmospheric pressure)
25	5	99.65	258.1

Main test

For the main study the metal block was heated to 245 °C. The capillaries containing the test item were placed into the apparatus and the temperature was raised at 0.5 °C/min heating rate until the boiling temperature was reached.

Three tests were carried out. At the end of the measurements the colour of the samples baceme yellow. The boiling temperature was determined and the boiling point of the test item was determined to be 256.7 ± 1.03 °C (95 % confidence interval) i.e. 529.9 K.

Atmospheric pressure, kPa (at the measuring)	Boiling point, °C (at standard atmospheric pressure)
99.65	256.4
99.65	256.6
99.66	257.2
Mean:	256.7
RSD (CV %):	0.2
Conf.int. (95 %)	1.03

Conclusions:

The boiling point of the test item was determined to be 256.7 ± 1.03 °C i.e. 529.9 K.

Executive summary:

A study was conducted according to OECD test guideline 103, Regulation (EC) No 440/2008 method A.2 and EPA OPPTS 830.8220 to determine the boiling point of the test item using the principle according to Siwoloboff. A small amount of the test item was filled in a capillary tube and was heated in the electronically temperature controlled sample block. In a preliminary test a boiling point of 245 °C was observed. This value was introduced as expected boiling temperature for the main test. The sample was heated from 245 °C at rate 0.5 °C/minute. The sample was observed visually for any possible changes in appearance, consistency and colour. The phase transition from liquid to vapour was deduced by the continuous formation of steam bubbles leaving the inserted boiling capillary. This determination was done in triplicate. The atmospheric pressure was recorded. The boiling point was determined to be 256.7 °C i.e. 529.9 K at 99.65 hPa.

Description of key information

The boiling point of the test item was determined to be 256.7 ± 1.03 °C i.e. 529.9 K.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

256.7 °C

Additional information

A study was conducted according to OECD test guideline 103, Regulation (EC) No 440/2008 method A.2 and EPA OPPTS 830.8220 to determine the boiling point of the test item using the principle according to Siwoloboff. A small amount of the test item was filled in a capillary tube and was heated in the electronically temperature controlled sample block. In a preliminary test a boiling point of 245 °C was observed. This value was introduced as expected boiling temperature for the main test. The sample was heated from 245 °C at rate 0.5 °C/minute. The sample was observed visually for any possible changes in appearance, consistency and colour. The phase transition from liquid to vapour was deduced by the continuous formation of steam bubbles leaving the inserted boiling capillary. This determination was done in triplicate. The atmospheric pressure was recorded. The boiling point was determined to be 256.7 °C i.e. 529.9 K at 99.65 hPa.