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Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Experimental starting date 13 February 2017 - Experimental completion date 15 July 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
other: The critical micelle concentration (CMC) of the test item was determined based on measurement of turbidity. The method will be based on Method A2 of ASTM international E 1148 – 02 guideline.
Version / remarks:
The critical micelle concentration (CMC) of the test item was determined since the test item is surface active and low soluble in water.
Deviations:
not applicable
GLP compliance:
yes (incl. QA statement)
Type of method:
other: The critical micelle concentration (CMC) of the test item was determined based on measurement of turbidity.
Water solubility:
< 10 mg/L
Conc. based on:
test mat. (total fraction)
Loading of aqueous phase:
25 mg/L
Temp.:
20 °C
pH:
7
Key result
Water solubility:
<= 10 mg/L
Conc. based on:
test mat. (total fraction)
Temp.:
20 °C
pH:
7
Remarks on result:
other: This value stands for the critical micelle concentration (CMC) of Quaternium-70.
Details on results:
In the concentration range of 25 to 240 mg/L, a linear relationship between response and test item concentration was observed. The equation of the regression line was: Y = 0.0581 x A – 0.5849 (r = 0.998, n = 8), where Y is the turbidity measured in NTU and A is the nominal concentration of the test item.
Since zero turbidity was not observed in any of the test solutions containing test item, the intercept at the x-axis was calculated. In this way, the CMC of the test item was estimated to be ≤ 10 mg/L.
Conclusions:
A method based on Method A2 of ASTM International E 1148 – 02 guideline was applied for the determination of the critical micelle concentration of Quaternium-70. The critical micelle concentration of the test item at 20.0 ± 0.3°C was estimated to be ≤ 10 mg/L.

Description of key information

A method based on Method A2 of ASTM International E 1148 – 02 guideline was applied for the determination of the critical micelle concentration of Quaternium-70, since the test item is surface active and low soluble in water. As zero turbidity was not observed in any of the test solutions containing test item, the intercept at the x-axis was calculated. In this way, the CMC of the test item was estimated to be ≤ 10 mg/L.

Key value for chemical safety assessment

Water solubility:
10 mg/L
at the temperature of:
20 °C

Additional information

Instead of water solubility, the critical micelle concentration of the test item at 20.0 ± 0.3°C was estimated to be ≤ 10 mg/L.