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EC number: 207-894-3 | CAS number: 499-83-2
pH
Administrative data
- Endpoint:
- pH
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- CIPAC MT 75 (Determination of pH Values)
- Deviations:
- not specified
- GLP compliance:
- no
Test material
- Reference substance name:
- Pyridine-2,6-dicarboxylic acid
- EC Number:
- 207-894-3
- EC Name:
- Pyridine-2,6-dicarboxylic acid
- Cas Number:
- 499-83-2
- Molecular formula:
- C7H5NO4
- IUPAC Name:
- pyridine-2,6-dicarboxylic acid
- Test material form:
- solid: crystalline
Constituent 1
Reagents
- Reagent:
- buffer solutions
Results and discussion
pH value
- Key result
- pH value:
- ca. 2
- Temp.:
- 24.7
- Concentration:
- ca. 1 vol%
Any other information on results incl. tables
Determination of pH-Value of 1% Test Substance
The following values were recorded.
Table3.1‑a pH-values
Parameter |
Determination 1 |
T (°C) |
Determination. 2 |
T (°C) |
Mean and Difference |
pH (instantly) |
2.01 |
24.7 |
2.02 |
24.8 |
|
pH (after1 min) |
2.01 |
24.7 |
2.01 |
24.8 |
|
Mean |
|
|
|
|
2.01 |
Difference |
0.00 |
|
0.01 |
|
0.00 |
Evaluation
The mean between both determinations gives the following pH-value:
pH-value (1% test substance): 2.01
Difference (1% test substance): 0.00
Validity
¨ The values of the single determinations showed no difference; therefore the demanded range of 0.10 is fulfilled.
¨ The pH of the standard buffer solution, pH = 9.180 was determined with no difference to the stated literature value
Applicant's summary and conclusion
- Conclusions:
- The determination was performed in duplicate.
Calibration of the pH-meter was performed using three buffer solutions of pH 4.006, 6.865, and 9.180, respectively.
In the control measurement, the pH-value of the standard buffer solution, pH 9.180 lay within the accepted range.
The pH-value of the 1% test item solution at 25.0 ± 0.3 °C was determined as 2.0. - Executive summary:
The determination was performed in duplicate.
Calibration of the pH-meter was performed using three buffer solutions of pH 4.006, 6.865, and 9.180, respectively.
In the control measurement, the pH-value of the standard buffer solution, pH 9.180 lay within the accepted range.
The pH-value of the 1% test item solution at 25.0 ± 0.3 °C was determined as 2.0
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