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EC number: 227-497-9 | CAS number: 5858-81-1
Nanomaterial dustiness
Administrative data
- Endpoint:
- nanomaterial dustiness
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- April - June 2021
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 021
- Report date:
- 2021
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EN 15051-2 (Workplace exposure. Measurement of the dustiness of bulk materials - Rotating drum method)
- GLP compliance:
- no
- Type of method:
- rotating cylinder
Test material
- Reference substance name:
- Disodium 3-hydroxy-4-[(4-methyl-2-sulphonatophenyl)azo]-2-naphthoate
- EC Number:
- 227-497-9
- EC Name:
- Disodium 3-hydroxy-4-[(4-methyl-2-sulphonatophenyl)azo]-2-naphthoate
- Cas Number:
- 5858-81-1
- Molecular formula:
- C18H12N2Na2O6S
- IUPAC Name:
- disodium 3-hydroxy-4-[(4-methyl-2-sulphonatophenyl)azo]-2-naphthoate
- Test material form:
- solid: nanoform, no surface treatment
Constituent 1
Reference material / nanomaterial and sample identification number
Reference
- Reference substance name:
- Unnamed
- IUPAC name:
- disodium 3-hydroxy-4-[(4-methyl-2-sulphonatophenyl)azo]-2-naphthoate
- Inventory number:
- InventoryMultipleMappingImpl [inventoryEntryValue=EC 227-497-9]
- CAS number:
- 5858-81-1
- Identity:
- 2-Naphthalenecarboxylic acid, 3-hydroxy-4-[(4-methyl-2-sulfophenyl)azo]-, disodium salt
- Identifier:
- IUPAC name
- Identity:
- disodium 3-hydroxy-4-[(E)-2-(4-methyl-2-sulfophenyl)diazen-1-yl]naphthalene-2-carboxylate
- Identifier:
- IUPAC name
- Identity:
- disodium 4-[(E)-2-(4-methyl-2-sulfophenyl)diazen-1-yl]-3-oxidonaphthalene-2-carboxylate
- Identifier:
- Colour Index
- Identity:
- CI 15850
- Identifier:
- common name
- Identity:
- 2-Naphthalenecarboxylic acid, 3-hydroxy-4-[(4-methyl-2-sulfophenyl)azo]-, disodium salt
- Identifier:
- common name
- Identity:
- D&C Red 6
- Identifier:
- common name
- Identity:
- Pigment Red 57
- Identifier:
- other: InChl
- Identity:
- 1S/C18H14N2O6S.2Na/c1-10-6-7-14(15(8-10)27(24,25)26)19-20-16-12-5-3-2-4-11(12)9-13(17(16)21)18(22)23;;/h2-9,21H,1H3,(H,22,23)(H,24,25,26);;/q;2*+1/p-2/b20-19+;;
- Identifier:
- other: Molecular formula
- Identity:
- C18H14N2O6S.2Na
- Identifier:
- other: SMILES notation
- Identity:
- c12c(c(c(C(=O)[O-])cc1cccc2)O)\N=N\c1c(cc(C)cc1)S(=O)(=O)[O-].[Na+].[Na+]
- Identity:
- disodium 3-hydroxy-4-[(4-methyl-2-sulfonatophenyl)diazenyl]-2-naphthoate
- Molecular formula:
- C18H12N2Na2O6S
- Molecular weight:
- 430.342
- SMILES notation:
- [Na+].[Na+].[O-]S(=O)(=O)c3cc(C)ccc3N=Nc1c2ccccc2cc(C([O-])=O)c1O
- InChl:
- InChI=1/C18H14N2O6S.2Na/c1-10-6-7-14(15(8-10)27(24,25)26)19-20-16-12-5-3-2-4-11(12)9-13(17(16)21)18(22)23;;/h2-9,21H,1H3,(H,22,23)(H,24,25,26);;/q;2*+1/p-2
Results and discussion
Dustiness index
- Key result
- Remarks on result:
- not determinable because of methodological limitations
- Remarks:
- EN15051-2 does not allow for the determination on the dustiness index, only the values for the inhalable, the thoracic and the respirable fraction. EN17199, only standard giving the dustiness index value not yet commercially available.
Any other information on results incl. tables
Inhalable fraction: 10375 mk/kg => High
Thoracic fraction: 995 mk/kg => Moderate
Respirable fraction: 145 mk/kg => Moderate
Applicant's summary and conclusion
- Conclusions:
- The dustiness potential of Pigment Red 57 / D&C Red 6 was determined using standard EN 15051-2. The substance exhibited a high dustiness potential for the inhalable fraction 10375 mg kg-1. The thoracic and respirable fractions are both classified as moderate with a dustiness potential of 995 mg kg-1 for the thoracic fraction and 145 mg kg-1 for the respirable fraction.
- Executive summary:
The dustiness potential of Pigment Red 57 / D&C Red 6 was determined using standard EN 15051-2. The substance exhibited a high dustiness potential for the inhalable fraction 10375 mg kg-1. The thoracic and respirable fractions are both classified as moderate with a dustiness potential of 995 mg kg-1 for the thoracic fraction and 145 mg kg-1 for the respirable fraction.
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