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EC number: 211-541-9 | CAS number: 660-68-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance has a low octanol water partition coefficient and the adsorption potential of this substance is related to this parameter
Reference
Description of key information
Low potential for adsorption based on low log Kow value (<3)
Key value for chemical safety assessment
- Koc at 20 °C:
- 87.1
Additional information
Diethylammonium chloride (CAS 660-68-4) has a very low partitioning coefficient of -1.3 mg/L (at 20°C) and thus low potential for adsorption. In accordance with Column 2 of REACH Annex VIII, the adsorption/desorption screening test does not need to be conducted.
However, the adsorption potential of Diethylammonium chloride (CAS 660-68-4) was further investigated for the needs of the chemical safety assessment.
Diethylammonium chloride (CAS 660-68-4) is a dimethylamine hydrochloride salt, that dissociates rapidly in water to basic diethylammonium cation and chloride anions, which are highly mobile, their adsorption potential can be neglected. Considering the ionizing property of the basic diethylamine, the adsorption potential was calculated using Franco and Trapp ‘s expressions (2008) on estimation of the organic carbon-water partitioning coefficient of ionisable organic substances. The log Kow of 0.58, its pKa of 10.84 and 3 different pH values (4, 7, 9) were used as input parameters for the calculation.
The following equation was used for the Koc calculation as suggested by the authors:
Koc =Φn * 100.37*logPn+1.70 +Φion * 10pKa^0.65*f^0.14
Where:
Φn = 1/(1+10(pH-pKa))
Pn: Kow of the neutral molecule (EpiWin)
pKa: 11.06 (more information in chapter 4.7)
Φion = 1-Φn
f: Ratio of concentration in octanol to total concentration: Kow (overall)/(Kow (overall) + 1)
The log Koc was calculated to be 1.84 at pH 4; 1.94 at pH 7 and 3.1 at pH 9. These values indicate that the adsorption potential of the substance to organic carbons in soil at neutral pH is low. According to the Guidance on Information Requirements and Chemical Safety Assessment, Chapter R.7.1.8.5 the log D value for the ionized molecule determined around the default pH of 7 is considered more relevant for chemical safety assessment. Therefore, the respective log Koc calculated at pH 7 has been used for the chemical safety assessment.
Reference:
Franco A. & Trapp S., 2008: Estimation of the soil-water partition coefficient normalized to organic carbon for ionizable organic chemicals. Environmental Toxicology and Chemistry, Vol. 27, No. 10, pp. 1995–2004.
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