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EC number: 286-061-6 | CAS number: 85186-76-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Flash point
Administrative data
Link to relevant study record(s)
- Endpoint:
- flash point of flammable liquids
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- ASTM D93 (Standard test methods for flash point by pensky-martens closed cup tester)
- GLP compliance:
- no
- Type of method:
- closed cup
- Flash point apparatus:
- Pensky-Martens apparatus
- Key result
- Flash point:
- 112.5 °C
- Atm. press.:
- 991 hPa
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The flash point was determined at 112.5°C at 991 hPa according to a ASTM D93 method.
- Endpoint:
- flash point of flammable liquids
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Read across category
- Key result
- Flash point:
- >= 170 - <= 213 °C
- Atm. press.:
- 1 013 hPa
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- Based on the experimental results of the source chemicals of the category, the flash point of the target substance "isostearate 2-ethylhexyl is considered to be ≥ 170 °C.
Referenceopen allclose all
Table1 :Results of key studies on source chemicals for flash point
Name of the substance |
CAS |
Fatty acids chain length |
Type of alcohol |
MW |
Appareance |
Flash Point |
Fatty acids, C8-16, 2- ethylhexyl esters |
135800-37-2 |
C8-16 |
2-ethylhexanol |
256.42 – 368.65 |
Liquid |
186°C at 1013mBar |
Fatty acids, coco, 2-ethylhexyl esters |
92044-87-6 |
C12-14 |
2-ethylhexanol |
312.53 – 340.60 |
liquid |
170°C at 1013hPa |
2-Ethylhexyl palmitate |
29806-73-3 |
C16 |
2-ethylhexanol |
368.65 |
Liquid |
210°C at 1013°C |
Fatty acids, C16-18 and C18-unsatd., 2-ethylhexyl esters |
85049-37-2 |
C16-18, C18:1 |
2-ethylhexanol |
368.65 – 396.7 |
Liquid |
No data |
Fatty acids, C16-18, 2-ethylhexyl esters |
91031-48-0 |
C16-18 |
2-ethylhexanol |
368.65 - 396.7 |
Liquid |
218°C at 1013Hpa |
2-Ethylhexyloleate |
26399-02-0 |
C18:1 |
2-ethylhexanol |
394.67 |
Liquid |
213°C at 1013hPa |
2-Ethylhexylstearate |
22047-49-0 |
C18 |
2-ethylhexanol |
396.7 |
Liquid |
210°C at 1013°C |
The physico-chemical properties of the category members are similar or follow a regular pattern over the category. All the members of the category have been tested for their flash point and they show flash points between 170 and 213°C. These very high values are related to the similarity of structures of the category members and the lack of flammability hazard.
Since the target substance is surrounded by the categories members, it can be deduced that its flash point will be ≥ 170 °C.
Description of key information
The Flash point of the target chemical "Isostearate 2 -ethylhexyl" was defined at 112,5°C measured with the Pensky-Martens cup tester.
Key value for chemical safety assessment
- Flash point at 101 325 Pa:
- 112.5 °C
Additional information
Justification and rationale of the category approach for the isostearate 2-ethyl hexyl :
This category group covers 2-ethyl hexyl esters linked with fatty acid chains (C8 to C18) unsatured and satured. This category includes monoconstituent substances and UVCB substances varying fatty acid chain length. This category was made in order to provide sufficient information for physicochemical, ecotoxicological and toxicological caracterisation of the Fatty acids, C14-18 and C18-unsatd., branched and linear, 2-ethylhexyl esters (CAS No 85186-76-1).
The category group includes:
- Fatty acids, C8-16, 2-ethylhexyl esters (CAS No 135800-37-2)
- Fatty acids, coco, 2-ethylhexyl esters (CAS No 92044-87-6)
- 2-Ethyl hexyl palmitate (29806-73-3)
- Fatty acids, C16-18 and C18-unsatd., 2-ethylhexyl esters (CAS No 85049-37-2)
- Fatty acids, C16-18, 2-ethylhexyl esters (CAS No 91031-48-0)
- 2-Ethylhexyl oleate (CAS No 26399-02-0)
- 2-Ethyl hexyl stearate (CAS No 22047-49-0)
Target substance for Category Approach : Fatty acids, C14-18 and C18-unsatd., branched and linear, 2-ethylhexyl esters (CAS No 85186-76-1)
In accordance with article 13 (1) of Regulation (EC) No. 1907.2006, “information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI are met. In particular for human toxicity, environmental fate and ecotoxicity, information shall be generated whenever possible by means other than vertebrate animal tests which includes the use of information from structurally related substances (grouping or read across)”. Therefore, the available experimental data were collected and evaluated according to Annex XI requirements.
Summary of available information
All the members of the category have been tested for their flash point and they show flash points between 170 and 213°C. These very high values are related to the similarity of structures of the category members and the lack of flammability hazard. Since the target substance is surrounded by the categories members, it can be deduced that its flash point will be ≥ 170 °C.
An experimental study on the target substance, isostearate 2 -ethylhexyl, was also performed according to the EU standard method by Pensky-Martens cup tester (only method and results provided) and it gives a value of 112,5°C.
Conclusion
According to the Regulation (EC) NO. 1907/2006, Annex XI, 1.5, A Read-Across Category for "Long Chain Fatty Acid, 2-ethylhexyl esters" was performed in order to provide information on Isostearate 2-Ethylhexyl .
This category was based on common and shared properties as:
- common functional group,
- common precursors and the likelihood of common impurities resulting from common process of manufacturing
- chemically structurally similar breakdown products obtained via the same biological processes into the organisms, and
- constant pattern in the changing of the potency of the properties across the category.
Based on the flash point obtained on the category members, it can be deduced that the target substance has a very high flash point, ≥ 170 °C, and doesn't present any inflammability hazard. Moreover an experimental study on the target substance, isostearate 2 -ethylhexyl, was also performed and it gives a value of 112,5°C. By applying a conservative approach, this lowest experimental value is chosen as the representative flash point for the substance "isostearate 2 -ethylhexyl".
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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