Registration Dossier

Administrative data

First-aid measures

Description of first aid measures. General information Avoid chance of exposure by any feasible way. After inhalation: Move the affected person to fresh air.If breathing becomes irregular or ceases, apply mouthtomouth resuscitation or artifical respiration immediately. Get medical attention. After skin contact: Immediately remove contaminated clothing, wash off the skin with plenty of water. After eye contact: Rinse the eyes with water for several minutes with eyelids open wide. Having rinsed the eyes, obtain ophthalmologic attention as soon as possible. After swallowing: Wash out the mouth with plenty of water, give plenty of water to
drink, then obtain medical attenton immediately. Information for doctor The physician must be informed on the time, type and extent of exposure. If needed, show the safety data sheet to the physician.

Fire-fighting measures

Extinguishing media: Suitable extinguishing media: Available extinguishing media: water spray, extinguishing powder, carbon dioxid, foam.
Unsuitable extinguishing media: Full waterjet are not suitable for extinguishing. Special hazards arising from the substance or mixture. Substance is combustible.
Combustion products: hydrogen chloride, sulphuroxides, nitrogenoxides, carbonmonoxide/ dioxide. Advice for firefighters: Outdoors stay on the weatherside
and extinguish from there. In closed places, and in case of wreck, wear fireproof working clothes and use selfcontained breathing apparatus.

Accidental release measures

Personal precautions, protective equipment and emergency procedures: Only the trained personnel in charge of release is allowed to be present at the site of spilling, wearing the prescribed protective equipments. Environmental precautions. Hinder the spilled substance from entering the soil, sewers or living water.
Methods and material for containment and cleaning up. Collect spilt substance aspiring to the lowest possible dustlevel. Put the collected substance into adequately labelled empties and transport them to the site of disposal, then wash the contaminated area with plenty of water.

Handling and storage

Precautions for safe handling: Handled it the compliance with good industrial hygiene and safety procedures. All work processes must always be designed so minimize or exclude the risk of exposure. Conditions for safe storage, including any incompatibilities. Store it in a cool, dry, wellventilated, free from direct sunlight
place. Specific end use(s): Intermediate (phase product of active pharmaceutical ingredient). Impurity/metabolite/degradation product of an active pharmaceutical ingredient.

Transport information

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Marine transport (IMDG)

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Exposure controls / personal protection

Appropriate engineering controls Hinder substance from entering the workplace. If it is inevitable, ensure mechanical exhaust ventilation /general and local as well. Individual protection measures / personal protective equipment: The personal protective equipment for the working process are determined by internal standards. Eye/face protection: Wear closed protection glasses. Skin protection: Closed protective clothing against particulate matter. Hand protection: Protective gloves made of neopren and butyl and nitrile. Respiratory protection: P3 dust mask. Environmental exposure controls In case of proper handling and using no environmental damage may be expected.

Stability and reactivity

Stable under normal circumstances. Sensitive to the following physical effects: intense light, intense. Incompatible materials strong mineral acids, strong basics, strong oxidisers heat.

Disposal considerations

Waste treatment methods: Suggestions for disposal procedures of the substance/product: Incineration in a special waste incineration plant. halogen, nitrogen, sulphur content of the substance should be considered when incinerated. Suggestions for disposal procedures of contaminated packaging (vessels): Flammable empties must be incinerated in waste increation plant, in compliance with local regulations.