Registration Dossier
Registration Dossier
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EC number: 251-598-7 | CAS number: 33619-92-0
Endpoint summary
Administrative data
Description of key information
The studies have not been conducted because the substance is classified as corrosive to the skin and is a strong base (pH > 11.5) in accordance with REACH Annex VII, 8.3., column 2.
Key value for chemical safety assessment
Skin irritation / corrosion
Link to relevant study records
- Endpoint:
- skin corrosion: in vitro / ex vivo
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is a strong acid (pH ≤ 2.0) or base (pH ≥ 11.5) and the available information indicates that it should be classified as skin corrosion (Category 1, 1A, 1B or 1C)
- Reason / purpose for cross-reference:
- reference to other study
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Link to relevant study records
- Endpoint:
- eye irritation: in vitro / ex vivo
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is classified as skin corrosion, leading to classification as serious eye damage (Category 1)
- Reason / purpose for cross-reference:
- reference to other study
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irreversible damage)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
The studies have not been conducted because the substance is classified as corrosive to the skin and is a strong base (pH > 11.5) in accordance with REACH Annex VII, 8.3., column 2.
Justification for classification or non-classification
Substance has a high pH of 12 -13 and a content of sodium hydroxide, which all warrants for the classification as corrosive to skin and eyes. It is probably also corrosive in the respirotoric organs, but exposure is highly unlikely because vapour pressure is low and it is used in low concentrations.
The substance is classified as H314 Skin Corr. 1C and H318 Eye Damage 1 according to Regulation (EC) No 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
