Registration Dossier
Registration Dossier
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EC number: 203-423-0 | CAS number: 106-68-3
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 27-01-2017 / 08-02-2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - HPLC Method)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7570 (Partition Coefficient, n-octanol / H2O, Estimation by Liquid Chromatography)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Octan-3-one
- EC Number:
- 203-423-0
- EC Name:
- Octan-3-one
- Cas Number:
- 106-68-3
- Molecular formula:
- C8H16O
- IUPAC Name:
- octan-3-one
- Test material form:
- liquid
- Remarks:
- colorless
- Details on test material:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Test item 207812/A, Batch No: EM14089719
- Purity 99.9%
- Expiration date of the lot/batch: 1 August 2017
- Purity test date: 7 July 2016
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: At room temperature
- Stability under test conditions: No information available
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficient
- Key result
- Type:
- log Pow
- Partition coefficient:
- 2.9
- Temp.:
- 32 °C
- pH:
- 7
Applicant's summary and conclusion
- Conclusions:
- The partition coefficient (Log Pow) of octan-3-one is 2.9 at 32°C at pH 7.
- Executive summary:
The test item octan-3-one has a partition coefficient (Log Pow) of 2.9 at 32°C at pH 7 according to the guideline OECD 117, EU Method A.8 and OPPTS 830.7570, using the HPLC method under GLP.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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