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Diss Factsheets
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EC number: 204-588-1 | CAS number: 122-98-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study performed according to national standards. Limitations in design and reporting but results considered reliable and adequate for assessment.
- Qualifier:
- according to guideline
- Guideline:
- other: DIN 38 412
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- no
- Test organisms (species):
- Leuciscus idus
- Details on test organisms:
- PRE-TEST CONDITIONS:
- Common name: Golden orfe
- Source: Fa. P. Eggers, Hohenwestedt bei Neumuenster, BRD (07-10-1980)
- Weight: 2.3 g
- Length: 6.4 cm
- Caging: in dechlorinated tap water; continuous aeration with oil-free air
- Feed: Fukosalm-anschlussfutter 1 (Fuko - Kraftfutterfabrik, Ulm, BRD) ad libitum
- Medical treatment during last 4 weeks: none
ACCLIMATION
- Acclimation period: 3 days - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96
- Remarks on exposure duration:
- h
- Hardness:
- 1.3-2.6 mmol/L
- Test temperature:
- 20±1°C
- pH:
- t=0h: 7.2-7.6
t=96h: 6.9-7.4 - Dissolved oxygen:
- t=0h: 8.1-9.1 mg O2/L
t=96h: 6.9-9.1 mg O2/L - Nominal and measured concentrations:
- - Nominal: 68.4, 100, 147, 215, 316, 464 anf 681 mg/L.
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 10L glass tanks (30 cm x 22 cm x 24 cm)
- Aeration: yes, continuous with oil-free air
- No. of organisms per vessel: 10 - Reference substance (positive control):
- yes
- Remarks:
- Chloracetamide
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 464 - < 681 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- - Deaths were observed only at the highest tested concentration of 681 mg/L (100% mortality within 1 hour after exposure).
- Symptoms such as narcose-like condition, site location and stagger were observed at the 464 mg/L test concentration. - Results with reference substance (positive control):
- - 48-h LC50: ca. 26 mg/L
- Reported statistics and error estimates:
- Finney, D.J. Probit analysis, Cambridge University Press (1971).
Reference
Description of key information
With high propability acutely not harmful to fish.
Key value for chemical safety assessment
Additional information
Acute toxicity to fish was tested in a study according to DIN 38412 dated March 3rd 1981 (BASF AG, study report number 80/476; non-GLP). The species under study was Gorden Orfe and the static test resulted in an LC50 >100 mg/L after a test duration of 96h.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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