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Diss Factsheets
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EC number: 942-166-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17.Aug. 2016 - 21. Apr. 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 5-10-A
- Expiration date of the lot/batch: 19.Oct. 2018
- Purity test date: a9. Oct. 2015
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: stored in a tightly closed vessel at 18.3 - 20.5 °C under dry conditions in the dark
- Stability under test conditions: assumed stable
- Solubility and stability of the test substance in the solvent/vehicle: assumed stable
- Reactivity of the test substance with the solvent/vehicle of the cell culture medium: assumed none
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
none - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): activated sludge from biologic sewage treatment plant (NW-Lachen-Speyerdorf)
- Pretreatment: The sludge was filtrated, washed with tap water (2x), then washed with and re-suspended in the test medium. it was then aerated until use.
- Dry matter: 4600 mg suspended solids/L
- Concentration of sludge: 25.0 mg/L
- Water filtered: no - Duration of test (contact time):
- ca. 28 d
- Initial conc.:
- ca. 26 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium:
Stock solution a: Potassium dihydrogen phosphate 8.5 g, Dipotassium hydrogen phosphate 21.75 g, Disodiumhydrogen phosphate dihydrate 33.4 g, Ammonium chloride 0.5 g, H2O demin. ad 1000 mL
Stock solution b: Calcium chloride 27.5 g, H2O demin. ad 1000 mL
Stock solution c: magnesium sulphate heptahydrate 22.5 g, H2O demin. ad 1000 mL
Stock solution d: Iron(III) chloride hexahydrate 0.25 g, Di-sodium-ethylene diaminetetraacetate dihydrate 0.4 g, H2O demin. ad 1000 mL
Test medium: Solution a 10 mL, Solution b 1 mL, Solution c 1 mL, Solution d 1 mL, H2O demin. ad 1000 mL
- Test temperature: 19.8 - 32.5 °C
- pH: ca. 7
- pH adjusted: no
- Aeration: vessels were aerated with purified, CO2-scrubbed, moitened air
- Suspended solids concentration: 25 mg/L inoculum
- Continuous darkness: not stated
- Other:
TEST SYSTEM
- Culturing apparatus: 2000 mL SCHOTT Flasks
- Number of culture flasks/concentration: 2
- Method used to create aerobic conditions: aeration of flasks with CO2 scrubbed air
- Measuring equipment: none attached
- Test performed in closed vessels due to significant volatility of test substance: no
- Test performed in open system: no
- Details of trap for CO2 and volatile organics if used: trapping of CO2 in 0.25 M NaOH. two scrubbers containing 100 mL each.
- Other:
SAMPLING
- Sampling frequency: 10 samples over 28 days
- Sampling method: pipetting 1 mL
- Sterility check if applicable: yes, apparatus blanks
- Sample storage before analysis: no specific storage conditions
- Other:
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
- Abiotic sterile control: yes
- Toxicity control: yes
STATISTICAL METHODS:
none - Reference substance:
- aniline
- Preliminary study:
- none
- Test performance:
- no unusual observations
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 3.7
- Sampling time:
- 2 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 9.7
- Sampling time:
- 4 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 19.8
- Sampling time:
- 7 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 29.7
- Sampling time:
- 9 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 36.1
- Sampling time:
- 11 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 43.2
- Sampling time:
- 15 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 50.9
- Sampling time:
- 18 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 59.5
- Sampling time:
- 23 d
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 64.5
- Sampling time:
- 29 d
- Details on results:
- Te 10-day-window began on day 4, at its end, 42 % degradation were reached, missing the pass level of 60 % given in the OECD guideline.
Because the test item is a mixture (i.e. UVCB), the 10-day window has not to be taken into accoung. Degradation surpassed 60 % within 28 days. - Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable, but failing 10-day window
- Conclusions:
- The test item Nomcort SG is considered as "ready biodegradable".
- Executive summary:
The test item Nomcort SG was tested using a concentration of nominally 20 mg organic carbon/L (corresponging to 25.8 mg Nomcort SG/L) in test medium following OECD 301B and EU-Method C.4 -C. Aniline was chosen as positive control.
Activated sludge was used as inoculum (concentration in the test 25.0 mg dry matter/L). The test was left running for 28 days.
All validity criteria were met. Degradation of the poistive control was 65 % after 9 days.
The following data were determined for the test item Nomcort SG:
10-day window day 4 -14
degradation at the end of 10-day window 42 %
degradation at the end of the test 65 %
pass level following guideline: 60 % at the end of 10-day window for pure substance respective 60 % at the end of the test for mixtures.
Because the test item is a mixture, the 10 -day window has not to be taken into account. As degradation surpassed 60 % in the course of the test, Nomcort SG is considered as readily biodegradable.
Reference
Description of key information
one OECD Guideline study available
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable but failing 10-day window
Additional information
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