1-ethoxy-2,3-difluorobenzene

Surface tension

Link to relevant study record(s)

Reference

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2000-10-10

Reliability:

1 (reliable without restriction)

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Version / remarks:

OECD Guideline No. 115 (1995)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Version / remarks:

EEC Commission Directive 92/69 - A5 method ( 1992)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

ring method

Key result

Surface tension:

63.1 mN/m

Temp.:

20 °C

Conc.:

228.6 mg/L

Test item:

Surface tension of the test item (uncorrected value):

Assay No. 1: 66.2 mN/m at 20.1 °C

Assay No. 2: 66.0 mN/m at 20.3 °C

Assay No. 3: 66.0 mN/m at 20.3 °C

Distilled water:

ϕo: 72.75 mN/m (surface tension of water at +20°C; value given in the literature),

ϕg: 75.48 mN/m (surface tension of sterilized for injection water at 20.1°C).

Calibration factor: ϕb = 0.964

 

ASSAY	MEASUREMENT (mN/m)	CORRECTION USING (ϕb (mN/m)	CORRECTION ACCORDING TO HAWKINS & JORDAN TABLE (mN/m)
1 2 3	66.2 66.0 66.0	63.7	63.1

TABLE: CORRECTION FOR MEASURED VALUES OF SURFACE TENSION

Applicable to aqueous solutions only: ϕb = 1 g/cm³

Experimental value mN/m	Calibration using riders	Calibration using water
60	55.2	59.1
62	57.2	61.3
64	59.2	63.4
66	61.2	65.5
68	63.2	67.7
70	65.2	69.9

Experimental value mN/m	Calibration using riders	Calibration using water
60	55.2	59.1
62	57.2	61.3
64	59.2	63.4
66	61.2	65.5
68	63.2	67.7
70	65.2	69.9

 

Conclusions:

The surface tension of the test item is 63.1 mN/m ± 0.1 mN/m at a concentration of 228.6 mg/L

Executive summary:

A study was conducted according to Directive 92/69/EEC Method A.5 and OECD Guideline No. 115 to determine the surface tension of an aqueous solution of the test item using the ring method. Therefore, a saturated solution at 90 % of the test substance in ultrapure water was prepared. Surface tension was determined at 20 °C. The surface tension of an aqueous solution the test item at 90 % saturation concentration (228.6 mg/L) was found to be 63.1 mN/m. As this value is higher than 60 mN/m, the test item is not classified as surface active substance.

Description of key information

The surface tension of the test item is 63.1 mN/m ± 0.1 mN/m at a concentration of 228.6 mg/L.

 

Key value for chemical safety assessment

Surface tension:

63.1

in mN/m at 20°C and concentration in mg/L:

228.6

Additional information

A study was conducted according to Directive 92/69/EEC Method A.5 and OECD Guideline No. 115 to determine the surface tension of an aqueous solution of the test item using the ring method. Therefore, a saturated solution at 90 % of the test substance in ultrapure water was prepared. Surface tension was determined at 20 °C. The surface tension of an aqueous solution the test item at 90 % saturation concentration (228.6 mg/L) was found to be 63.1 mN/m. As this value is higher than 60 mN/m, the test item is not classified as surface active substance.