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Diss Factsheets
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EC number: 946-945-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2002
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP / guideline study without deviations
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Details on sampling:
- The test concentration was measured at 0 and 72 hours.
- Vehicle:
- yes
- Details on test solutions:
- 0 and 5mg/L, applied dissolved in dimethylformamide.
- Test organisms (species):
- Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
- Details on test organisms:
- Scenedesmus subspicatusCHODAT, Strain No. 86.81 SAG. Algae had been grown in the RCC laboratories under standardized conditions.
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 72 h
- Post exposure observation period:
- no
- Hardness:
- 0.24 mml l-1 as CaCO3
- Test temperature:
- 23°C (flasks in water bath)
- pH:
- 8.2 at the beginning of the test, increasing to 9.0.
- Dissolved oxygen:
- not available
- Salinity:
- not available
- Nominal and measured concentrations:
- Nominal: 5 mg/L
Measured:
1.96 mg/L at the beginning of the test (39% of nominal)
5.28 mg/L at the end of the test (106% of nominal) - Details on test conditions:
- - Photoperiod: Continuous
- Light intensity and quality: Illumination at about 8600 Lux - Reference substance (positive control):
- yes
- Remarks:
- potassium dichromate
- Key result
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- > 5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- EC10
- Effect conc.:
- > 5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- EC10
- Effect conc.:
- > 5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- biomass
- Key result
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- biomass
- Details on results:
- The analytical determined test item concentration in the analyzed test medium samples amounted to 1.96 mg /L (39% of nominal) at the start of the test. On the surface of the test medium an oily film was observed at the start of the test. However, after 24 hours, the test medium was clear and no remarkable observations were made concerning the appearance of the test medium. In the test medium, incubated under conditions during the test period (but without algae), 106% of the nominal concentration was found at the end of the test.
The mean algal cell densities in the test medium were at all counting dates identical with or even slightly higher than those in parallel solvent control cultures. Thus d-Phenothrin had no inhibitory effect on the growth of Scenedesmus subspicatus after the exposure period of 72-h at a concentration of 5 mg/L. This test concentration was therefore determined as the 72-h NOEC. The NOEC might even be higher but concentrations in excess have not been tested.
The 72-hour LOEC, EbC10, EbC50 and ErC10, ErC50 could not be calculated due to the absence of a toxic effect of the test item - Results with reference substance (positive control):
- The positive control is used in the lab at least once a year to validate the systems.
- Validity criteria fulfilled:
- yes
- Conclusions:
- It can be concluded that d-Phenothrin had no toxic effect on the algae up to its water solubility limit (<2 mg/L).
- Executive summary:
d-Phenothrin had no toxic effect on the algae up to its water solubility limit (<2 mg/L).
Reference
Cell concentration data
Nominal concentration (mg/L) |
|
Density of algal cells (cell number x 104/mL) after |
|||||
24 h |
48 h |
72 h |
|||||
Control |
|
4.1 |
4.0 |
6.7 |
5.9 |
46.7 |
46.2 |
4.3 |
3.4 |
5.8 |
6.1 |
50.3 |
51.7 |
||
3.1 |
3.4 |
7.0 |
6.4 |
44.3 |
43.5 |
||
A. M. S. D. |
3.72 0.42 |
6.32 0.38 |
47.12 3.60 |
||||
Solvent control |
|
3.4 |
3.5 |
5.7 |
5.4 |
38.5 |
38.6 |
3.4 |
3.4 |
6.9 |
6.9 |
42.3 |
40.2 |
||
3.5 |
3.6 |
6.1 |
5.8 |
42.5 |
42.0 |
||
3.8 |
3.6 |
6.5 |
6.3 |
50.7 |
50.3 |
||
5.0 |
4.1 |
6.1 |
6.0 |
46.2 |
45.5 |
||
3.8 |
3.6 |
6.4 |
6.5 |
48.0 |
46.8 |
||
A. M. S. D. |
3.73 0.42 |
6.22 0.47 |
44.30 4.40 |
||||
5.0 |
|
4.2 |
3.6 |
6.3 |
6.9 |
50.9 |
52.0 |
3.5 |
3.5 |
5.7 |
5.3 |
40.5 |
41.1 |
||
4.5 |
3.6 |
6.3 |
5.8 |
50.5 |
49.4 |
||
A. M. S. D. |
3.82 0.28 |
6.05 0.55 |
47.40 5.76 |
A.M.: arithmetic mean
S.D.: standard deviation
Description of key information
d-Phenothrin was assessed for toxicity towards freshwater algae in a study performed according to OECD 201 and was found having no inhibitory effect on the algae up to its water solubility limit (>5 mg/L nominal concentration).
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 5 mg/L
- EC10 or NOEC for freshwater algae:
- 5 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.