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Diss Factsheets
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EC number: 203-003-7 | CAS number: 102-07-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017-03-21 to 2017-03-22
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Qualifier:
- according to guideline
- Guideline:
- other:
- Version / remarks:
- CIPAC MT 187
- Principles of method if other than guideline:
- The analysis was conducted initially using a visual microscope and was then undertaken more formally using a Laser Diffraction Particle Size Analyser. The sample was observed under 3 conditions: Direct observation, under a microscope with 32 x magnification, under a microscope with 400 x magnification. The physical characteristics of the material were recorded, noting such items as shape and size distribution. Following this the Malvern Mastersizer 2000 Laser Diffraction Analyser was used. Five runs of the method were conducted to ensure repeatability of results.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- Laser scattering/diffraction
- Type of particle tested:
- primary particle
- Type of distribution:
- volumetric distribution
Test material
- Reference substance name:
- 1,3-diphenylurea
- EC Number:
- 203-003-7
- EC Name:
- 1,3-diphenylurea
- Cas Number:
- 102-07-8
- Molecular formula:
- C13H12N2O
- IUPAC Name:
- 1,3-diphenylurea
- Test material form:
- solid
Constituent 1
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
White or off-white solid
Batch number: 506001
Purity / composition: 98 %
Relative density: 1.25 (supplied by Charles River Laboratories)
Chemical name (IUPAC), synonym or trade name: Diphenylurea
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
Test item storage: At room temperature
Stable under storage conditions until: 24 March 2018 (retest date)
Results and discussion
- Mass median aerodynamic diameter:
- 17.088 µm
- Geometric standard deviation:
- 0.007
- Remarks on result:
- other: 30.04% volume of sample is seen to be < 10 um
Particle sizeopen allclose all
- Percentile:
- D10
- Mean:
- < 5.007 µm
- St. dev.:
- 0.042
- Remarks on result:
- other: % STDVP 0.8
- Percentile:
- D50
- Mean:
- < 15.284 µm
- St. dev.:
- 0.103
- Remarks on result:
- other: % STDVP 0.7
- Percentile:
- D90
- Mean:
- < 39.256 µm
- St. dev.:
- 0.423
- Remarks on result:
- other: % STDVP 1.1
Any other information on results incl. tables
Standard visual observation: Sample observed to be a fine, off-white powder which formed some clusters.
Observation at 32 x magnification: The particles appeared to be irregular shaped crystals. The smallest individual particle size was approximately 3 μm and the largest individual size was approximately 61 μm.
Observation at 400 x magnification: The sample was observed to be made up of single crystalline particles.
Applicant's summary and conclusion
- Conclusions:
- The mass median aerodynamic diameter was determined to be 17.088 um.
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