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EC number: 249-707-8 | CAS number: 29590-42-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
The ready biodegradability of IOA was assessed in two non-GLP studies utilizing OECD TG301D (Closed Bottle Test) and measuring IOA concentration via GC analyses as well as oxygen depletion. In the key study, IOA was readily biodegraded, with 93%-95% depletion of dissolved oxygen by day 28. In the supporting study, IOA was also readily biodegraded, showing 64% - 69% depletion of dissolved oxygen by day 28.
In the key study, IOA underwent substantial primary degradation by day 5 according to GC analysis, with mineralization lagging. Dissolved oxygen measurements demonstrate that IOA was readily biodegraded, with 93%-95% depletion of dissolved oxygen by day 28. This study was conducted in accord with a draft version of test guidance OECD301D. Differences between this and the currently-adopted method are slight, but the test data were too sparse to permit evaluation of either the 10-day or the 14-day windows for biodegradability. Also, the test was not conducted according to GLP criteria. It is therefore classified as reliable with restrictions.
In the supporting study, IOA was again seen to undergo substantial primary degradation by day 5 according to GC analysis, with mineralization lagging. Dissolved oxygen measurements demonstrate that IOA was readily biodegraded, with 64% - 69% depletion of dissolved oxygen by day 28. Test data were too sparse to permit evaluation of either the 10-day or the 14-day windows for biodegradability. This study was nominally conducted in accord with a draft version of test guidance OECD301D. However, the report provides summary data only and has few details on conduct of the study. Also, the test was not conducted according to GLP criteria. Study reliability could therefore not be classified. However, this study clearly supports the results of the key study. Therefore, IOA is considered to be readily biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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