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Diss Factsheets
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EC number: 201-184-7 | CAS number: 79-19-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- OECD 202
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: The Notice on the Test Method Concerning New Chemical Substances
- Deviations:
- no
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Vehicle:
- not specified
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method:Test solutions were prepared by mixing a stock solution of the test substance, which was prepared by dissolving the substance in test water. - Test organisms (species):
- Daphnia sp.
- Details on test organisms:
- TEST ORGANISM
- Feeding during test: No - Test type:
- semi-static
- Water media type:
- other: dechlorinated tap water
- Limit test:
- no
- Total exposure duration:
- 48 h
- Test temperature:
- 19.9 - 20.1 ºC
- Nominal and measured concentrations:
- Nominal:30, 20, 13, 8.9, 5.9 mg/L,(geometric ratio 1.5) control
- Details on test conditions:
- TEST SYSTEM
- Material, size, headspace, fill volume: Test solution volume 400 mL/concentration (100 mL/vessel)
- Aeration: No
- Renewal rate of test solution (frequency/flow rate): After 24 hours of exposure
- No. of organisms per vessel: 5 (20 /concentration)
- No. of vessels per concentration (replicates):4
OTHER TEST CONDITIONS
- Photoperiod: Room light
- Light intensity: 16 hours light / 8 hours dark
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- ca. 12 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- not specified
- Basis for effect:
- mobility
- Remarks on result:
- other: 95% CL= 10 - 14mg/L
- Details on results:
- - Lowest concentration causing 100 % immobility (48 h): > 30 mg/L
- Highest concentration causing 0 % immobility (48 h): 5.9 mg/L
All results were based on the nominal values. - Validity criteria fulfilled:
- not specified
- Conclusions:
- The test item has effective concentration EC50 (48h) of 12mg/L . (Acute toxicity on daphnia magna)
- Executive summary:
Based on available data from National instititute of technology and evaluation (NITE) test item was tested to the toxicity to freswater species of Daphnia Magna, in the nominal concentration: 30, 20, 13, 8.9, 5.9 mg/L , 0 mg/L (control) and the temperature 19.9 - 20.1 ºC according the OECD TG 202, followed GLP principles. Test was performed in semi-static condition during 48 hours. Five organism per vessels (20 per concentrations) were used. Test solutions were prepared by mixing a stock solution of the test substance, which was prepared by dissolving the substance in test water.The Effective concentration EC50 (48h) of 12 mg/L based on mobility was evaluated.
Reference
Description of key information
Key study: Based on available data from National instititute of technology and evaluation (NITE) test item has Effective concentration EC50 (48h) of 12 mg/L based on mortality.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 12 mg/L
Additional information
Key study:OECD TG 202, followed GLP principles.
Based on available data from National instititute of technology and evaluation (NITE) test item was tested to the toxicity to freswater species of Daphnia Magna, in the nominal concentration: 30, 20, 13, 8.9, 5.9 mg/L , 0 mg/L (control) and the temperature 19.9 - 20.1 ºC . Test was performed in semi-static condition during 48 hours. Test solutions were prepared by mixing a stock solution of the test substance, which was prepared by dissolving the substance in test water.The Effective concentration EC50 (48h) of 12 mg/L based on mobility was evaluated.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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