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EC number: 911-296-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1988-07-25 to 1988-07-29
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Meets National Standard Methods (DIN) with acceptable restrictions Read across was performed with Laurylacrylat 12/14 (mixture of laurylacrylate (CAS No.: 2156-97-0) and tetradecylacrylate (CAS No.: 21643-42-5) . Please refer to IUCLID section 13 for read across justification.
- Qualifier:
- according to guideline
- Guideline:
- other: German industrial standard test guideline DIN 38 412, part L 15, JUNE 1982
- Deviations:
- no
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION
- Method: The dose was chosen based on a range finding study.
- The product was added to the test water without any pretreatment; subsequently the fish were placed into the aquaria. Based on the results of a range finding study (LC 50 after 96 h: between 100 and 1000 mg/L) the concentrations, spaced by a factor of about 2.2, were fixed as follows: 100, 215, 464 and 1000 mg/L.
- Vehicle/solvent: none
- Stability of the test chemical solutions: no data - Test organisms (species):
- Leuciscus idus
- Details on test organisms:
- TEST ORGANISM
- Common name: Goldorfe
- Strain: Leuciscus Idus L., Goden variety
- Source: Fischzucht Paul Eggers, 2354 Hohenwestedt, Germany
- Length at study initiation: 7.7 cm (Range: 6.9 -8.9)
- Weight at study initiation: 4.3 g (Range: 2.8 - 6.6)
- Feeding during test : 1 day before and during exposure (withdrawal of food)
ACCLIMATION
- Acclimation period: 3 days
- Acclimation conditions: same as test
- Type and amount of food: yes, ad libitium (Growing Feed F/B 50, SSniff Spezialdiaeten GmbH, D-4770 Soest, FRG) - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Hardness:
- 2.5 mmol/L
- Test temperature:
- 20 °C
- pH:
- 7.5 - 7.9
- Dissolved oxygen:
- 7.3 - 8.5 mg/L
- Nominal and measured concentrations:
- Nominal concentration: 0, 100, 215, 464, 1000 mg/L
No concentrations were measured. - Details on test conditions:
- TEST SYSTEM
- Test vessel: all-glass aquaria
- Type: open
- Material, size, headspace, fill volume: 30x 22 x 24 cm, 10 L
- Aeration: aeration with oil-free air
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 1
- No. of vessels per control (replicates): 1
- Biomass loading rate: 4.3 g fish/L
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: reconstituted freshwater according to DIN 38412, part 11
- Ca/mg ratio: 4:1
- Intervals of water quality measurement: 1, 4, 24, 48, 72, 96 hours
OTHER TEST CONDITIONS
- Photoperiod: 16:8 hour light/dark
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : mortality, symptoms - Duration:
- 96 h
- Dose descriptor:
- LC100
- Effect conc.:
- 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 215 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- ca. 460 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- 215 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- - Biological Observations: At the test concentration of 464 mg/L a number of fish showed apathy after 48, 72 and 96 hours. At the highest substance concentration (1000 mg/L) tumbling and narcotic-like state were observed after 24 h among the fish.
- Lowest test substance concentration causing 100% mortality: 1000 mg/L
- Mortality of controls: none - Results with reference substance (positive control):
- Positive control of animals conducted with chloroacetamide: LC 50 after 48 h: about 26 mg/L
This lethal concentration corresponds to the normal sensitivity. - Reported statistics and error estimates:
- Probit analysis according to Finney DJ (1971). Probit Analysis, Cambr. Univ. Press, 3rd Ed.
- Endpoint:
- short-term toxicity to fish
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- other information
- Reason / purpose for cross-reference:
- read-across source
Referenceopen allclose all
Description of key information
No acute fish toxicity study is available on the registered substance (Reaction mass of C12-C13 acrylates, EC Number 911-296-4). However, experimental data are available on an analogue substance (Reaction mass of C12-C14 acrylates, CAS 84238-60-8).
In an experimental study conducted according to the DIN 38 412, Part L 15 (June 1982), the LC50 was determined to be ca. 460 mg/L and the NOEC was equal to 215 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 460 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.