Registration Dossier
Registration Dossier
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EC number: 431-870-3 | CAS number: -
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 28th September - 29th October 1999
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: done under GLP and OECD method
- Qualifier:
- according to guideline
- Guideline:
- other: Directive 92/69/EEC Part C, Test C7;OECD Guideline No.111.
- GLP compliance:
- yes
- Transformation products:
- not measured
- % Recovery:
- 90.545
- pH:
- 4
- Temp.:
- 50 °C
- Duration:
- 2.4 h
- % Recovery:
- 92.96
- pH:
- 7
- Temp.:
- 50 °C
- Duration:
- 2.4 h
- % Recovery:
- 93.47
- pH:
- 9
- Temp.:
- 50 °C
- Duration:
- 2.4 h
- % Recovery:
- 0
- pH:
- 4
- Temp.:
- 50 °C
- Duration:
- 5 d
- % Recovery:
- 0.085
- pH:
- 7
- Temp.:
- 50 °C
- Duration:
- 5 d
- % Recovery:
- 1.525
- pH:
- 9
- Temp.:
- 50 °C
- Duration:
- 5 d
- pH:
- 4
- Temp.:
- 25 °C
- DT50:
- 1 - <= 365 d
- pH:
- 7
- Temp.:
- 25 °C
- DT50:
- 1 - <= 365 d
- pH:
- 9
- Temp.:
- 25 °C
- DT50:
- 1 - <= 365 d
- Validity criteria fulfilled:
- yes
- Conclusions:
- The results indicate that at 25ºC, the substance will possess a half-life time of between 1 day and 1 year at pH 4, pH 7 and pH 9.
- Executive summary:
After a period of 2.4 hours, the test substance underwent <10% hydrolysis at 50°C and at pH 4, 7 and 9 indicating a half life of greater than 1 day at these pH values at 25°C. After a period of 5 days, the test substance underwent >98% hydrolysis at pH 4, 7 and 9 at 50°C indicating a half life of less than 1 year at 25°C. Therefore, the half life of the test substance at 25°C is between 1 day and 1 year at pH 4, 7 and 9.
Reference
Description of key information
After a period of 2.4 hours, the test substance underwent <10% hydrolysis at 50°C and at pH 4, 7 and 9 indicating a half life of greater than 1 day at these pH values at 25°C. After a period of 5 days, the test substance underwent >98% hydrolysis at pH 4, 7 and 9 at 50°C indicating a half life of less than 1 year at 25°C. Therefore, the half life of the test substance at 25°C is between 1 day and 1 year at pH 4, 7 and 9.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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