Registration Dossier
Registration Dossier
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EC number: 290-271-3 | CAS number: 90106-48-2 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Secale cereale, Gramineae.
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Remarks:
- The study was conducted according to an internationally recognised method. No deviation was reported. Test substance is adequately specified. Therefore full validation applies.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
Test material
- Reference substance name:
- Rye, ext.
- EC Number:
- 290-271-3
- EC Name:
- Rye, ext.
- Cas Number:
- 90106-48-2
- IUPAC Name:
- Oligosaccharides and polysaccharides of glucose from Rye
- Test material form:
- solid: particulate/powder
- Details on test material:
- - Appearance: white powder
- Storage In darkness at room temperature
- Batch: 16 167
- Manufacturing date: June 2016
- Expiry date: June 2018
Constituent 1
Results and discussion
Water solubility
- Key result
- Water solubility:
- ca. 541.3 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 1 117 g/L
- Temp.:
- 30 °C
- pH:
- ca. 7
- Details on results:
- The water solubility of COHELISS AT was determined as 541 g/L at 30 ± 0.5°C (pH = 7).
The conditions of the test were: a loading rate of 1117 ± 2 g/L and a water content of 6.7% w/w (dry matter result obtained on the powder).
Applicant's summary and conclusion
- Conclusions:
- According to OECD method No. 105, the water solubility of COHELISS AT was determined as 541 g/L at 30 ± 0.5°C (pH = 7), for a loading rate of 1117± 2 g/L and considering that the test item contains 6.7%w/w of water (dry matter result obtained on the powder).
- Executive summary:
A non-GLP study using flask method according to OECD method 105 and EU. A.6. was conducted to determine the water solubility of COHELISS AT.
The water solubility of COHELISS AT was determined as 541 g/L at 30 ± 0.5°C (pH = 7).
The conditions of the test were: a loading rate of 1117 ± 2 g/L and a water content of 6.7% w/w (dry matter result obtained on the powder).
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