Registration Dossier
Registration Dossier
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EC number: 274-397-6 | CAS number: 70209-99-3
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 23 Sep 1974
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Version / remarks:
- Method A-11
- Deviations:
- not specified
- GLP compliance:
- no
- Specific details on test material used for the study:
- Test material identified as: FAT 40068/A; Lanasol blue 36 100 %
- Analytical monitoring:
- no
- Vehicle:
- yes
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- none
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Test temperature:
- 15 °C
- pH:
- 6-8
- Dissolved oxygen:
- 4.8 - 6.4 mg/L
- Nominal and measured concentrations:
- 100, 200 mg/L nominal concentration.
- Reference substance (positive control):
- no
- Key result
- Duration:
- 48 h
- Dose descriptor:
- other: TL50
- Effect conc.:
- 140 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- 8/8 fish survived at 24 and 48h - 100 mg/L
0/8 fish survived at 24 and 48h - 200 mg/L - Validity criteria fulfilled:
- yes
- Conclusions:
- The 48h TL50 of FAT 40068/A in this fish acute toxicity test was determined to be 140 mg/L.
- Executive summary:
The acute fish toxicity test was performed using a methodology equivalent or similar to OECD Guideline 203. Fish were exposed to FAT 40068/A for 48 hours at following concentrations: 100 mg/L and 200 mg/L. All the exposed fish were found dead at 200 mg/L, while no mortality was seen with 100 mg/L concentration.
Based on these findings, the 48h TL50 of FAT 40068/A in this fish acute toxicity test was determined to be 140 mg/L.
Reference
Description of key information
The acute fish toxicity test was performed using a methodology equivalent or similar to OECD Guideline 203. Fish were exposed to FAT 40068/A for 48 hours at following concentrations: 100 mg/L and 200 mg/L. All the exposed fish were found dead at 200 mg/L, while no mortality was seen with 100 mg/L concentration. Based on these findings, the 48h TL50 of FAT 40068/A in this fish acute toxicity test was determined to be 140 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 140 mg/L
Additional information
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