Registration Dossier
Registration Dossier
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EC number: 253-675-0 | CAS number: 37811-72-6
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Readily biodegradable: ≥67% in 28 days (CO2 evolution, OECD 301B); read across
Key value for chemical safety assessment
Additional information
Experimental data investigating the biodegradability of isobutyl laurate (CAS 37811-72-6)is not available. The assessment was therefore based on a study conducted with the structural analogue substances isopentyl laurate (CAS 6309-51-9) and isopropyl laurate (CAS 10233-13-3) as part of a read across approach, which is in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5. Further justification is given within the overall summary chapter 6.1 and within the analogue justification section 13.
The biodegradability of the source substance isopentyl laurate (CAS 6309-51-9) was tested according to OECD Guideline 301B (Junghans, 2008). A degradation rate of 100% based on CO2 evolution was determined after 28 days of exposure. The biodegradation of the test item reached 80% at the end of the 10-day window. The ready biodegradability of the second read across substace isopropyl laurate (CAS 10233-13-3) was tested according to OECD guideline 301D (van Ginkel and Stroo, 1993). The test substance was inoculated with active sludge. The oxygen consumption of the inoculum was followed for 28 days. During the test period the biodegradation reached 67%.The 10-day window criterion was met.
Based on the results of the read across studies isopentyl laurate (CAS37811-72-6) is considered readily biodegradable according to the OECD criteria.
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