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EC number: -
CAS number: -
Study acute toxicity
studies are available for Alkylated naphthalene, EC Number 700-826-8,
The fish acute toxicity test was
performed according to OECD guideline No. 203 under GLP compliance. The
result showed the test substance induced no visible or lethal effects in
carp at 0.020 mg/l, being the average measured exposure concentration in
a WAF prepared at a loading rate of 100 mg/l (NOEC). The 96 h-LC50
exceeded 0.020 mg/l, being the average measured exposure concentration
in a WAF prepared at a loading rate of 100 mg/l.
The acute toxicity test with Daphnia
magna was performed according to OECD guideline No. 202 under GLP
compliance. The result showed the test substance did not induce acute
immobilisation of Daphnia magna at 0.62 mg/l, being the average measured
concentration in a WAF prepared at a loading rate of 100 mg/l after 48
hours of exposure (NOEC). The 48 h-EC50 exceeded 0.62 mg/l, being the
average measured concentration in a WAF prepared at a loading rate of
Algal growth inhibition test was performed according to OECD guideline
No. 201 under GLP compliance. The result showed no reduction of growth
rate or inhibition of yield was recorded at any of the WAFs of Alkylated
naphthalene tested. Both the EC50 for growth rate reduction (72 h-ERC50)
and the EC50 for yield inhibition (72 h-EYC50)
exceeded 0.2 mg/l, being the Time Weight Average concentration in a WAF
prepared at a loading rate of 100 mg/l.
Due to the poor water solubility of test substance (below 25 μg/L), the
exposure to the aquatic compartment is negligible. In addition, it is
sufficient for the classification and PBT/vPvB assessment based on
available information. Thus,
no further long-term aquatic toxicity tests will be necessary.
Based on the acute toxicity tests results of
three trophic levels (fish, Daphnia and algae), the
short-term L/EC50 values are all above 100 mg/l, thus the
loading rate of 100 mg/l is used as the key value for PNECwater
Due to lack of aquatic toxicity no
hazard for the aquatic compartment is expected but nevertheless a PNEC
was derived as input for sediment and soil PNEC calculation based on the
Although no bioaccumulation is expected
through the food chain, a PNEC oral was derived, based on the result of
the OECD422 study with rats.
The substance does not meet the criteria for classification as given in
Commission Regulation (EU) No 286/2011 amending for the second time
Regulation (EC) No 1272/2008. The substance is not classified for
environmental hazards on the basis of the available information on
ecotoxicology, environmental fate and physical-chemical properties.
However, as the threshold for classification with R53 according to DSD
(Directive 67/548/EEC) regarding bioaccumulation is a BCF of 100 rather
than 500 as in CLP (the BCF for this substance was estimated being 102
according to a valid QSAR model), the substance requires classification
according to DSD with R53.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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