Registration Dossier
Registration Dossier
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EC number: 239-555-0 | CAS number: 15520-05-5
Endpoint summary
Administrative data
Description of key information
After single oral application the LD 50 in female rats was determined as 1157 mg/kg bw. After single dermal exposure to 2000 mg/kg bw no mortality or other systemic effects were observed. Local irritation occurred at the site of application.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 1 157 mg/kg bw
- Quality of whole database:
- reliable without restriction
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
- Quality of whole database:
- reliable without restriction
Additional information
After single oral application the LD 50 in female rats was determined as 1157 mg/kg bw. After single dermal exposure of male and female Wistar rats to 2000 mg/kg bw no mortality or other systemic effects were observed. Local irritation occurred at the site of application.
Classification: acute oral toxicity cat. 4 due to the observed LD 50 in female rats
No classification for dermal systemic toxicity.
Justification for classification or non-classification
Classification: acute oral toxicity: Cat. 4 H 302
Justification: Observed LD 50 in female rats
No classification for dermal systemic toxicity.
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