Registration Dossier
Registration Dossier
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EC number: 435-580-8 | CAS number: 56553-60-7
Endpoint summary
Administrative data
Description of key information
Additional information
The test substance is known to rapidly hydrolyse in contact with water to form boric acid (CAS 10043-35-3), acetic acid (CAS 64-19-7), sodium acetate (CAS 127-09-3 ), and hydrogen (CAS 1333-74-0). For the hydrolysis products boric acid, acetic acid and sodium acetate relevant aquatic toxicity data was gathered from the ECHA dissemination dossier (d.d. 2014 -11 -19) and tabulated below.
Aquatic toxicity data for boric acid:
Study |
Species |
Endpoint |
Effect value |
Fish acute toxicity |
L. limanda (salt water) |
96-h LC50 |
74 mg/L* |
Fish chronic toxicity |
I. punctatus |
9-d LC10 |
3.5 mg/L** |
Aquatic invertebrates acute toxicity |
H. azteca |
96-h LC50 |
64 mg/L*** |
Aquatic invertebrates chronic toxicity |
D. magna |
21-d NOEC |
6 mg/L**** |
Algae acute |
S. capricornutum |
72-h EC50 |
52.4 mg/L ***** |
Algae chronic |
S. capricornutum |
72-h NOEC |
17.5 mg/L ***** |
| Micro organisms | O. bimarginata | 72 h NOEC | 10 mg/L ****** |
* lowest effect concentration of two WoE endpoints.
** lowest effect value of a total of 11 WoE endpoints for both boric acid and various boron/borate species.
*** lowest effect concentration of a total of 23 WoE endpoints for both boric acid and various boron/borate species.
**** lowest effect concentration of a total of 10 WoE endpoints for both boric acid and various boron/borate species.
***** lowest effect concentrations from one of two WoE endpoints.
****** lowest effect concentration from a total of 9 WoE enpoints for both boric acid and various boron/borate species.
Aquatic toxicity data for acetic acid:
Study |
Species |
Endpoint |
Effect value |
Fish acute toxicity |
O. mykiss |
96 -h LC50 |
>300.82 mg/L * |
Aquatic invertebrates acute toxicity |
D. magna |
48 -h EC50 |
>300.82 mg/L * |
Algae acute |
S. costatum |
72 -h EC50 |
>300.82 mg/L * / ** |
| Micro organisms | P. putida | 16 -h NOEC | 850 mg/L*** |
* Tests performed with potassium acetate, values for acetate ion.
** Two key studies available however, one graded reliability 4.
*** Supporting study, no key study available. Two effect values were stated in the record. Lowest has been selected.
Aquatic toxicity data for sodium acetate:
Study |
Species |
Endpoint |
Effect value |
Fish acute toxicity |
D. rerio |
96 -h LC50 |
>100 mg/L |
Aquatic invertebrates acute toxicity |
D. magna |
48 -h EC50 |
>1000 mg/L * |
Algae acute |
S. costatum |
72 -h EC50 |
>417.92 mg/L** |
| Algae chronic | S. costatum |
72 -h NOEC | 417.92 mg/L** |
| Micro organisms | P. putida | 16 -h EC50 | 7200 mg/L |
* Two key studies available, value of test with sodium acetate selected.
** Read-across with potassium acetate. Values have been corrected for molecular weight of sodium acetate.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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