Registration Dossier
Registration Dossier
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EC number: 215-925-7 | CAS number: 1453-58-3
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
In vitro studies were GLP-compliant and of high quality (Klimisch 1). Therefore, there is no reason to believe that these results would not be applicable to humans.
Justification for selection of genetic toxicity endpoint
No study is selected , since all three in vitro tests are negative.
Short description of key information:
For 3-Methylpyrazole three in vitro test for genetic toxicity are available:
1. Ames-test: negative result
2. In vitro chromosome abberration test: negative result
3. HPRT-test for point mutations: negative results
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
3 -Methylpyrazole has not to be classified as mutagenic substance.
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