Registration Dossier
Registration Dossier
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EC number: 201-302-7 | CAS number: 80-70-6
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Depending on local conditions and existing concentrations, disturbances in the biodegradation process of activated sludge are possible.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 350 mg/L
- EC10 or NOEC for microorganisms:
- 17 mg/L
Additional information
In a GLP short-term respiration test according to OECD 209 conducted with 1,1,3,3 -Tetramethylguanidine (CAS 80 -70 -6) a 3h-EC20 of 48 mg/L (3h-EC10 = 17 mg/L; 3h-EC50 = 350 mg/L) was obtained for oxygen consumption, based on the nominal test concentrations (BASF SE, report no. 08G0014/17G046, 2017). The test was performed using domestic activated sludge.
In conclusion, depending on local conditions and existing concentrations, disturbances in the biodegradation process of activated sludge are possible.
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