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EC number: 910-245-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2016-02-05 to 2016-04-02
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- The study was conducted with the Water Accommodated Fraction (WAF) of Frit. When Firt is mixed with water, the souble fraction is this test substance.
- Analytical monitoring:
- no
- Details on sampling:
- Substance undergoes rapid hydrolysis in water, therefore analytical moitoring was not possible
- Vehicle:
- yes
- Details on test solutions:
- All test solutions were prepared separately at loading rates ranging from 1.0 to 100 mg/L in water applying a 30 minute period of ultrasonic waves followed by a two-day period of magnetic stirring. Thereafter, the resulting mixtures were filtered over a 0.45 µm membrane filter (Whatman; RC55). The resulting Water Accommodated Fractions (WAFs) were clear and colourless and used as test solutions. The pH of the highest WAF was set from 10.3 to 8.8 in the combined limit/ range finding test and from10.3 to 8.6 in the limit test with 1M HCl.
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Daphnia magna (Crustacea, Cladocera) (Straus, 1820), at least third generation, obtained by acyclical parthenogenesis under specified breeding conditions. For the test, young daphnids with an age of < 24 hours were selected from parental daphnids of more than two weeks old.
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Remarks on exposure duration:
- combined limit/range finding test
- Test temperature:
- 18-22°C
- pH:
- WAF (mg/L) Start (t=0 h) End (t=48 h)
pH O2 pH O2
Control 7.8 9.4 8.0 9.1
100 8.5 8.7 7.7 9.0 - Details on test conditions:
- The test conditions remained within the limits prescribed by the study plan (pH: 6.0-8.5, not varying by more than 1.5 units; oxygen: 3 mg/L at the end of the test).
The temperature continuously measured in a temperature control vessel varied between 20 and 21°C during the test, and complied with the requirements as laid down in the study plan (18-22°C, constant within 2°C) - Reference substance (positive control):
- yes
- Remarks:
- potassium dichromate
- Duration:
- 48 h
- Dose descriptor:
- EL50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks:
- WAF
- Basis for effect:
- mobility
- Details on results:
- Range finder - In the lowest WAF tested, i.e. prepared at a loading rate of 1.0 mg/L, 10 and 20% of the daphnids were immobilised after 24 and 48h, respectively. No immobility was observed in the two higher WAFs tested. In the control group, 45% of daphnids were immobilised after 48h. This response exceeded the 10% tolerance limit for immobility in the control group as described in the study plan. The results of this test were used as a range-finder.
No effects on mobility of daphnids were observed at a loading rate of 100 mg/L for the limit test. Both the 24 and 48 hour EL50 were determined to be >100 mg/L (WAF). - Validity criteria fulfilled:
- yes
- Conclusions:
- The study met the acceptability criteria prescribed by the study plan and was considered valid.
The 48h-EL50 was beyond the range tested, i.e. exceeded loading rate of 100 mg/L. - Executive summary:
Acute Toxicity Study in Daphnia magna was conducted with Silicic acid (H4SiO4), zirconium (4+) salt (1:1), reaction products with sodium hydroxide.
The study procedures described were based on the OECD guideline No. 202, 2004. In addition, the procedures were designed to meet the test methods of theCommissionRegulation (EC) No440/2008,Part C.2, 2008 and the OECD series on testing and assessment number 23, 2000.
The batch of test item tested was a brown powder not completely soluble in test medium at the loading rates initially prepared.The test item was a UVCB substance. No correction was made for the purity/composition of the test item.
A Water Accommodated fraction (WAF) was prepared at a loading rate of 100 mg/L applying a 30 minute period of ultrasonic waves followed by a two-day period of magnetic stirring. Thereafter, the resulting mixture was filtered over a 0.45 µm membrane filter and used as limit concentration. The final test solution was clear and colourless. The pH of the WAF was set from 10.3 to 8.6 with 1 M HCl.
A limit test was performed, based on the results of a preceding combined limit/range-finding test.In the limit test, twenty Daphnia per group (four replicates, 5 daphnids per vessel) wereexposed to an untreated control and to a WAF prepared at a loading rate of 100 mg/L. The total exposure period was 48h. No samples were taken to analytically confirm exposure concentrations.
The study met the acceptability criteria prescribed by the study plan and was considered valid.
The 48h-EL50 was beyond the range tested, i.e. exceeded loading rate of 100 mg/L.
Reference
Description of key information
The 48h-EL50 was beyond the range tested, i.e. exceeded loading rate of 100 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
The 48h-EL50 was beyond the range tested, i.e. exceeded loading rate of 100 mg/L.
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