Sodium 2-hexyloxyethanolate

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

migrated information: read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Guideline study with acceptable restrictions

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1990

Report date:

1990

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: DIN 38412, part L11

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

2-hexyloxyethanol

EC Number:

203-951-1

EC Name:

2-hexyloxyethanol

Cas Number:

112-25-4

Molecular formula:

C8H18O2

IUPAC Name:

2-(hexyloxy)ethanol

Details on test material:

- Name of test material (as cited in study report): N-hexylglykol
- Purity: no data given

Sampling and analysis

Analytical monitoring:

no

Test solutions

Vehicle:

no

Details on test solutions:

PREPARATION AND APPLICATION OF TEST SOLUTION
- Method: A stock solution was prepared (1000 mg/L which was diluted in order to receive the required concentrations (geometrical series, factor 1.8)

Test organisms

Test organisms (species):

Daphnia magna

Details on test organisms:

TEST ORGANISM
- Source: Dr. U. Noack-Laboratorium, Hildesheim, Germany
- Method of breeding: 1 individuum per vial (filled with 70 ml)
- Feeding during test: no data


ACCLIMATION
- Acclimation period: no data

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

48 h

Test conditions

Test temperature:

21 °C

pH:

7.52 - 7.69

Dissolved oxygen:

8.3 - 8.6 mg/l

Nominal and measured concentrations:

Nominal concentrations: 0, 32, 58, 100, 180, 320 and 580 mg/L

Details on test conditions:

TEST SYSTEM
- Test vessel: beaker
- Type: open
- Material, size, fill volume: glass, 50ml, 20 ml
- Aeration: none
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 4

TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: according to DIN 38412 part II, 8.2

OTHER TEST CONDITIONS
- Light intensity: diffuse, 10 (micro E/qm x s)

EFFECT PARAMETERS MEASURED: mobility after 3, 6, 24 and 48 h

Reference substance (positive control):

yes

Remarks:

potassium dichromate

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

48 h

Dose descriptor:

EC0

Effect conc.:

58 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

Effect concentrations 2

Duration:

48 h

Dose descriptor:

EC100

Effect conc.:

320 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

Effect concentrations 3

Duration:

48 h

Dose descriptor:

EC50

Effect conc.:

145 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

Results with reference substance (positive control):

EC0= 1.0 mg/l
EC50= 1.45 mg/L
EC100 3.2 mg/L

Any other information on results incl. tables

Immobile individuals (%) after x hours (cumulative results)

Nominal concentration (mg/L)	3	6	24	48
0	0	0	0	0
32	0	0	0	0
58	0	0	0	0
100	0	0	0	0
180	35	45	70	70
320	100	100	100	100
580	100	100	100	100