Registration Dossier
Registration Dossier
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EC number: 208-060-1 | CAS number: 506-93-4
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018-08-29
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- GLP compliance:
- not specified
- Other quality assurance:
- ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
- Type of method:
- Laser scattering/diffraction
- Type of particle tested:
- primary particle
- Type of distribution:
- volumetric distribution
- Mass median aerodynamic diameter:
- 133.91 µm
- Remarks on result:
- not determinable
- Key result
- Percentile:
- D10
- Mean:
- 62.72 µm
- Remarks on result:
- other: SD not determined
- Key result
- Percentile:
- D25
- Mean:
- 117.8 µm
- Remarks on result:
- other: SD not determined
- Key result
- Percentile:
- D50
- Mean:
- 242.13 µm
- Remarks on result:
- other: SD not determined
- Key result
- Percentile:
- D75
- Mean:
- 415.73 µm
- Remarks on result:
- other: SD not determined
- Key result
- Percentile:
- D90
- Mean:
- 591.98 µm
- Remarks on result:
- other: SD not determined
- Key result
- Percentile:
- other: D100
- Mean:
- 1 030 µm
- Remarks on result:
- other: SD not determined
- Conclusions:
- 26 % of the particles have a diameter < 125 µm, 13 % < 71µm.
As the substance is highly water soluble (>100g/l), particles inhaled are quickly solved. - Executive summary:
26 % of the particles have a diameter < 125 µm, 13 % < 71µm.
As the substance is highly water soluble (>100g/l), particles inhaled are quickly solved.
Reference
Description of key information
26 % of the particles have a diameter < 125 µm, 13 % < 71µm.
Additional information
According to company data of AlzChem (2018) 26 % of the particles of Guanidine Nitrate have a diameter < 125 µm, 13 % < 71µm. As the substance is highly water soluble (>100g/l), particles inhaled are quickly solved.
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