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Diss Factsheets
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EC number: 206-991-8 | CAS number: 409-21-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Additional physico-chemical information
Administrative data
- Endpoint:
- other: analysis of extractable organic substances and soluble inorganic elements
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 21 January - 05 February 2008
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study generated according to internationally accepted guidelines.
Data source
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- other: ISO 10993-12
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: ISO 10993-18
- Deviations:
- no
- GLP compliance:
- yes
- Remarks:
- except ICP investigation
Results and discussion
Any other information on results incl. tables
Investigation of Extractable Organic Substances (GC/MS Fingerprint)
Water Extracts: No product-related peaks were detected in the GC/MS fingerprint chromatograms of the water extracts of the investigated three different silicon carbide powders as compared to the chromatograms of the negative control (pure extraction medium).
Isopropy Alcohol Extracts: No product-related peaks were detected in the GC/MS fingerprint chromatograms of the isopropyl alcohol extracts of the investigated three different silicon carbide powders as compared to the chromatograms of the negative control (pure extraction medium).
n-Hexane Extracts: No product-related peaks were detected in the GC/MS fingerprint chromatograms of the n-hexane extracts of the investigated three different silicon carbide powders as compared to the chromatograms of the negative control (pure extraction medium).
ICP-lnvestigation
The ICP screening of the water extract of the silicon carbide powder 'TRS-9899-100F' showed the presence of the following elements.
Water extract of negative control: B, Ba, Ca, K, Mg, Na, Si.
Water extract of silicon carbide powder: B, Ba, Ca, K, Mg, Na, Si, Al, S, V, Sr.
After the screening the aqueous solutions (extract and negative control) were subjected to the quantification of the identified metallic ions. As the elements boron (B), and sodium (Na) were present in the negative control as well as in the test item extract to a similar content and were most likely extracted from the used glass-vials, a quantification was not performed. The individual results are given in the following table:
Sample | amount in µg/ml | Al | Ba | Ca | K | Mg | S | Si | Sr | V |
negative control | <0.01 | <0.01 | 0.02 | <0.1 | <0.01 | 0.1 | 0.3 | <0.01 | <0.01 |
SiC, TRS-9899-100F | 0.07 | 0.01 | 3.2 | 1.1 | 0.12 | 2.2 | 5.5 | 0.02 | 1.1 |
In the table below the determined amounts of inorganic elements were related to the 1 g of powder:
Sample | amount in µg/g powder | Al | Ba | Ca | K | Mg | S | Si | Sr | V |
negative control | <0.05 | <0.05 | 0.10 | <0.5 | <0.05 | 0.5 | 1.5 | <0.05 | <0.05 |
SiC, TRS-9899-100F | 0.35 | 0.05 | 16.0 | 5.5 | 0.6 | 11.0 | 27.5 | 0.10 | 5.5 |
Applicant's summary and conclusion
- Conclusions:
- It can be concluded, that the GC/MS fingerprint investigation showed that no product related volatile or semivolatile organic substance could be detected in the several liquid extracts of the three different silicon carbide powders.
In the ICP investigation and in comparison to pure w ater, amounts of silicon, calcium, sulfur, potassium and vanadium w ere detected in the water extract of the silicon carbide powder 'TRS-9899-100F'. Furthermore, traces of barium, strontium, aluminum and magnesium could be detected.
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