Orthophosphoric acid

Exposure related observations in humans: other data

Administrative data

Endpoint:

exposure-related observations in humans: other data

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Secondary reference based on the Payne review

Cross-reference

Reason / purpose for cross-reference:

reference to other study

Data source

Reference

Reference Type:

other company data

Title:

Unnamed

Year:

1987

Materials and methods

Endpoint addressed:

repeated dose toxicity: inhalation

Test material

Test material information

Constituent 1

Reference substance name:

Orthophosphoric acid

EC Number:

231-633-2

EC Name:

Orthophosphoric acid

Cas Number:

7664-38-2

Molecular formula:

H3O4P

IUPAC Name:

phosphoric acid

Results and discussion

Results:

According to the review of Payne in toxicological information, the Renke et al, 1987 study state that, the health of workers was investigated in a phosphoric acid division type of process unspecified) of phosphate fertilizer plant. The incidence of bronchial and peribronchial changes was not clearly significantly greater than for non-exposed office staff in the same factory.
No information on exposure concentration.
No information on duratoin of exposure.
No possibility to conclude about toxic effects of phosphoric acid from that study.

Applicant's summary and conclusion

Conclusions:

Study inconclusive as no information on concentration and duration of exposure is reported (based on secondary source).