Registration Dossier
Registration Dossier
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EC number: 232-188-7 | CAS number: 7789-75-5
Toxicity to aquatic plants other than algae
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic plants other than algae
- Remarks:
- Lemna
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- A read-across justification has been provided in Section 13.
- Reason / purpose for cross-reference:
- read-across source
- Duration:
- 7 d
- Dose descriptor:
- IC50
- Effect conc.:
- 803.39 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Remarks:
- CaF2
- Basis for effect:
- other: frond growth
- Duration:
- 7 d
- Dose descriptor:
- IC50
- Effect conc.:
- 1 337 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Remarks:
- CaF2
- Basis for effect:
- other: dry weight
- Details on results:
- Lemna is relatively insensitive to fluoride.
- Results with reference substance (positive control):
- Acceptable limits for control performance.
- Validity criteria fulfilled:
- yes
- Conclusions:
- Lemna minor was found to be relatviely insensitive to fluoride with an IC50 value (frond number) of 391 mg/L F. This relates to a IC50 of 803 mg CaF2/L.
- Executive summary:
A 7 -day study was conducted on Lemna minor to assess the toxicity of fluoride in the presence of chloride and in hard water. Lemna minor was found to be relatively insensitive to fluoride with an IC50 value (frond number) of 391 mg/L F. This relates to 803 mg CaF2/L.
Reference
Description of key information
No studies are available for calcium fluoride. Available studies on fluoride were used as read-across source. Effective concentrations were recalculated taking in account the different molecular weight of the source and target substance.
A 7 -day study was conducted on Lemna minor to assess the toxicity of fluoride in the presence of chloride and in hard water. Lemna minor was found to be relatively insensitive to fluoride with an IC50 value (frond number) of 391 mg/L F. This relates to 803.39 mg CaF2/L.
Key value for chemical safety assessment
- EC50 for freshwater plants:
- 803.39 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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