Registration Dossier
Registration Dossier
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EC number: 208-156-3 | CAS number: 513-35-9
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Studies in Animals
The skin sensitization potential of 2 -methyl-2 -butene (2M2B) was assessed using the guinea-pig maximization method of Magnusson and Kligman (1969). None of the animals showed any positive reactions 24 or 48 hours after the removal of the challenge patch, it can be concluded that 2M2B is not a skin sensitizer in guinea pigs (SRC, 1980).
Human data
No data available
Migrated from Short description of key information:
2-methylbut-2-ene (2M2B) is not a skin sensitiser.
Respiratory sensitisation
Endpoint conclusion
- Additional information:
Respiratory Tract
No specific respiratory sensitisation tests have been conducted in animals. There is no evidence of respiratory sensitisation from existing animal study data.
Studies in Humans
No data available
Migrated from Short description of key information:
There are no specific studies available, but also no evidence of respiratory sensitisation from existing data.
Justification for classification or non-classification
No classification of 2 -methylbut-2 -ene for sensitisation is warranted under DSD or CLP.
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