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Diss Factsheets
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EC number: 234-685-4 | CAS number: 12023-91-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
- Ames-test according to OECD Guideline 471 (Bacterial Reverse Mutation Assay)
- in-vitro gene mutation study according to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)
- in-vitro cytogenicity study according to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)
Three studies were performed to examine potential genetic toxicity of strontium ferrite:
Strontium ferrite showed to be not mutagenic in the Ames-test bacterial test systems either with or without exogenous metabolic activation at the dose levels investigated. Strontium ferrite is also not genotoxic in the mammalian cells test system according to OECD 476 (mouse lymphoma assay) either with or without exogenous metabolic activation at the dose levels investigated. Too, strontium ferrite is not cytotoxic - does not produce chromosome aberration - in the mammalian cells test system according to OECD 473 (chromosome aberration test) either with or without exogenous metabolic activation at the dose levels investigated.
A study on in-vivo genetic toxicity is not required due to Annexes IX and X REACH as strontium ferrite did not show a positive result in any of the in-vitro genotoxicity studies performed as to annexes VII and VIII.
Strontium ferrite is not considered as a mutagen.
Short description of key information:
Strontium ferrite is not mutagenic in the Ames-test bacterial test systems either with or without exogenous metabolic activation at the dose levels investigated. Strontium ferrite is also not genotoxic in the mammalian cells test system according to OECD 476 (mouse lymphoma assay) either with or without exogenous metabolic activation at the dose levels investigated. Too, strontium ferrite is not cytotoxic - does not produce chromosome aberration - in the mammalian cells test system according to OECD 473 (chromosome aberration test) either with or without exogenous metabolic activationat the dose levels investigated
Strontium ferrite is not considered as a mutagen.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
Strontium ferrite does not show mutagenic properties (genetic toxicity). Thus classification is not required.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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