Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 203-686-1 | CAS number: 109-60-4
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Documentation insufficent for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Zur Toxikologie der Loesungsmittel. (Several Ester, Aceton, Methylalkohol.)
- Author:
- Flury F, Wirth W
- Year:
- 1 933
- Bibliographic source:
- Archiv f. Gewerbepath. u. Gewerbehyg. 5, 1-90, 1933
Materials and methods
- Study type:
- study with volunteers
- Endpoint addressed:
- other: serval endpoints addressed
- Principles of method if other than guideline:
- Short term inhalation study with volunteers (5 min, 4 subjects).
- GLP compliance:
- no
Test material
- Reference substance name:
- Propyl acetate
- EC Number:
- 203-686-1
- EC Name:
- Propyl acetate
- Cas Number:
- 109-60-4
- Molecular formula:
- C5H10O2
- IUPAC Name:
- propyl acetate
Constituent 1
Method
- Type of population:
- other: volunteers, unspecified
- Subjects:
- 2-4
- Ethical approval:
- not specified
- Route of exposure:
- inhalation
- Reason of exposure:
- intentional
- Exposure assessment:
- measured
Results and discussion
Any other information on results incl. tables
After exposure to a concentration of 1000 mg/m3 (236 ml/m3), very slight irritation effects in eyes, nose and pharynx were observed.
After exposure to 15000 mg/m 3 (3500 ml/m3) slight irritation effects in eyes, nose, pharynx and upper respiratory tract were observed.
Additionally, cold feeling, dryness in the pharynx and upper respiratory tract and slight discharge was observed only in the high dose.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
