Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 430-550-0 | CAS number: 1671-49-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to terrestrial plants: long-term
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17 Jan 2005 to 10 Feb 2005
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP compliant, guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 208 (Terrestrial Plants Test: Seedling Emergence and Seedling Growth Test)
- Deviations:
- no
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations: Samples were taken from stock solutions (50898 ppm NMST) and control.
- Sampling method: Triplicate samples were taken from the stock solution and a single sample from the control.
- Sample storage conditions before analysis: Not reported - Vehicle:
- yes
- Details on preparation and application of test substrate:
- - Method of mixing into soil (if used): Stock solutions (pre-mixed with 200 g sand and 100 g bulk artificial soil) mixed with bulk soil in a soil mixer
- Controls: Blank and vehicle control
- Chemical name of vehicle (organic solvent, emulsifier or dispersant): Acetone
- Concentration of vehicle in test medium (stock solution and final test solution): Not reported
- Evaporation of vehicle before use: Not reported - Species:
- Avena sativa
- Plant group:
- Monocotyledonae (monocots)
- Details on test organisms:
- - Common name: Oats
- Plant family: Poaceae
- Variety: Armor
- Source of seed: Gries Seed Farm Inc., Fremont, OH, USA
- Prior seed treatment/sterilization: None
- Historical germination of seed (germination of seed lot tested): Not reported
- Seed storage: Not reported - Species:
- Brassica napus
- Plant group:
- Dicotyledonae (dicots)
- Details on test organisms:
- - Common name: Oilseed Rape
- Plant family: Brassicaceae
- Variety: None provided
- Source of seed: Johnny's Selected Seeds, Winslow, ME, USA
- Prior seed treatment/sterilization: None
- Historical germination of seed (germination of seed lot tested): Not reported
- Seed storage: Not reported - Species:
- Pisum sativum
- Plant group:
- Dicotyledonae (dicots)
- Details on test organisms:
- - Common name: Pea
- Plant family: Fabaceae
- Variety: Laxton Progress #9
- Source of seed: Mayer Quality Seeds, Baltimore, MD, USA
- Prior seed treatment/sterilization: None
- Historical germination of seed (germination of seed lot tested): Not reported
- Seed storage: Not reported - Test type:
- seedling emergence toxicity test
- Study type:
- semi-field study
- Substrate type:
- artificial soil
- Limit test:
- no
- Total exposure duration:
- 21 d
- Test temperature:
- Min: 16.70 °C, Max: 26.96 °C, Mean: 20.50 °C, SD: 0.63 °C
- pH:
- 7.4
- Moisture:
- Not reported
- Details on test conditions:
- TEST SYSTEM
- Testing facility: Wildlife International Ltd. glasshouse facility
- Test container (type, material, size): Plastic pots, 16 cm in diameter, 12 cm deep
- Amount of soil: 1940 cm3 per pot
- Method of seeding: Template used to gently compact the soil and leave ten uniform holes. One seed was then planted in each hole. A. sativa and P. sativum seeds were planted at an approximate depth of 20 mm, while B. napus seeds were planted at an approximate depth of 6 mm.
- No. of seeds per container: 10
- No. of plants (retained after thinning): No thinning reported.
- No. of replicates per treatment group: 4
- No. of replicates per control: 4
- No. of replicates per vehicle control: 4
SOURCE AND PROPERTIES OF SUBSTRATE (if soil)
- Collection procedures: Not applicable, artifical soil
- Composition (if artificial substrate): 50% sand, 29% silt, 21% clay, organic matter 1.7%
- Organic carbon (%): 1.0%
- Maximum water holding capacity (in % dry weigth): Not reported
- CEC: Not reported
- Pretreatment of soil: Not reported
- Storage (condition, duration): Not reported
NUTRIENT MEDIUM (if used)
- Description: A slow-release fertilizer was added to provide nutrients essential for plant growth
GROWTH CONDITIONS
- Photoperiod: 16 hours light minimum
- Light source: Natural + Artificial (high-pressure sodium)
- Light intensity and quality: Min: 7.9 moles photosynthetically active radiation/day, Max: 17.9 moles photosynthetically active radiation/day, Mean: 13.7 moles photosynthetically active radiation/day, SD: 2.9 moles photosynthetically active radiation/day.
- Day/night temperatures: Daily maxima and minima reported.
Min: 16.70 °C, Max: 16.96 °C, Mean: 20.50 °C, SD: 0.63 °C
- Relative humidity (%):
Min: 11.06 %. Max: 55.08 %, Mean: 27.52 %, SD: 6.95 %.
- Wind velocity: Not applicable
- Air exchange rate: Not reported.
- Watering regime and schedules:
- Water source/type: Well water from glasshouse facility
- Volume applied: Not reported
- Interval of applications:
B. napus and A. sativa: Days 1, 5, 9, 12, 14, 16, 18, 20, 21
P. sativum: Days 2, 5, 10, 14, 18, 21
- Method of application: Subirrigation
- Any pest control method/fertilization (if used): Not reported
ACCLIMATION PERIOD: Not applicable
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : Seedling emergence at Days 7, 14 and at test termination. Seedling growth (dry weight, height), survival and condition measured at test termination.
- Phytotoxicity rating system (if used): 0 - 100 Rating scale adapted from: Frans, Robert E. and Ronald E. Talbert. 1977. Design of Field Experiments and the Measurement and Analysis of Plant Responses. Pages 15-23 in B. Truelove, ed. Research Methods in Weed Science. Southern Weed Science Society, Auburn University, Alabama.
VEHICLE CONTROL PERFORMED: Yes, acetone solvent only
TEST CONCENTRATIONS
- Spacing factor for test concentrations: 10
- Justification for using less concentrations than requested by guideline: Not applicable
- Test concentrations: 0, 10, 100 mg test substance/kg soil dry weight - Nominal and measured concentrations:
- 0, 10, 100 mg test substance/kg soil dry weight
Analytical monitoring of the stock solution returned values at 101% of nominal (see Table 1). Results are reported as nominal concentrations - Reference substance (positive control):
- no
- Species:
- Avena sativa
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- > 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- seedling emergence
- Species:
- Avena sativa
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- seedling emergence
- Species:
- Avena sativa
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- seedling emergence
- Species:
- Avena sativa
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- > 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: survival
- Species:
- Avena sativa
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: survival
- Species:
- Avena sativa
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: survival
- Species:
- Avena sativa
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Remarks:
- height
- Species:
- Avena sativa
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 10 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Remarks:
- height
- Species:
- Avena sativa
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- 44.6 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Remarks:
- height
- Species:
- Avena sativa
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 10 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Remarks:
- biomass
- Species:
- Avena sativa
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 1 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Remarks:
- biomass
- Species:
- Avena sativa
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- 13.9 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Remarks:
- biomass
- Species:
- Brassica napus
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- > 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- seedling emergence
- Species:
- Brassica napus
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- seedling emergence
- Species:
- Brassica napus
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- seedling emergence
- Species:
- Brassica napus
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- > 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: survival
- Species:
- Brassica napus
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: survival
- Species:
- Brassica napus
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- 55 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: survival
- Species:
- Brassica napus
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 10 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Remarks:
- height
- Species:
- Brassica napus
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 1 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Remarks:
- height
- Species:
- Brassica napus
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- 10.1 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Remarks:
- height
- Species:
- Brassica napus
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 10 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Remarks:
- biomass
- Species:
- Brassica napus
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 1 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Remarks:
- biomass
- Species:
- Brassica napus
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- 50.5 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Remarks:
- biomass
- Species:
- Pisum sativum
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- > 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- seedling emergence
- Species:
- Pisum sativum
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- seedling emergence
- Species:
- Pisum sativum
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- seedling emergence
- Species:
- Pisum sativum
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- > 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: survival
- Species:
- Pisum sativum
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: survival
- Species:
- Pisum sativum
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: survival
- Species:
- Pisum sativum
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Remarks:
- height
- Species:
- Pisum sativum
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 10 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Remarks:
- height
- Species:
- Pisum sativum
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- 66.8 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Remarks:
- height
- Species:
- Pisum sativum
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Remarks:
- biomass
- Species:
- Pisum sativum
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 10 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Remarks:
- biomass
- Species:
- Pisum sativum
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- 50.5 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Remarks:
- biomass
- Details on results:
- SEED GERMINATION
- Percent seed germination: Not reported
- Root length: Not reported
- Root discolouration/malformation: Not reported
SEEDLING EMERGENCE
- Percent seedling emergence: Observed. Defined as the presence of visible plant tissue at the surface of the soil.
- Percent survival: Observed.
- Plant height: Seedling height was measured with a ruler to the nearest whole centimeter from the surface of the soil to the tip of the tallest leaf
- Dry weight: Measured.
- Abnormal seed development or appearance: Seedling condition assessed on rating system (Table 2), considering all relevant observable characteristics.
INJURY RATING SYSTEM: See table 2 - Results with reference substance (positive control):
- Not applicable
- Reported statistics and error estimates:
- Dunnett's test was used to establish the LOEC and NOECby determining which treatment groups differed significantly (p<0.05) from the control group. Mean seedling emergence, survival, biomass, and height of the control and treatment groups were compared using the DUNNETT option of the GLM (general linear model) procedure of SAS (SAS Institiute 1999).
Determination of effect rates (ER estimates) and their confidence limits was done using the non-linear regression analysis of Bruce and Versteeg
(Bruce and Versteeg 1992) when reductions in test endpoints among one or more treatment groups were 25% or more relative to control means. Analyses were conducted using the NLIN procedure of SAS. ER25 and ER50 were defined as the test substance application rates that caused an 25%/50% change in the treatment group mean emergence, survival, dry weight or height relative to the control group. ERx estimates were calculated using nominal test concentrations and treatment group mean values with the following equation:
if C > 0 R= R0 * ¿[(log(ERx)-log(C))/¿ +Zx]
if C = 0 R= R0
where:
R = the predicted biotic response at concentration C
R0 = the predicted biotic response for controls
¿[ ] = the cumulative area under the standard, normal distribution
log(ERx) = the logarithm of the predicted ER giving an x percentage of decrease in the biological parameter vs. the
control
Zx = the normal deviate above which x percentage of the area of the standard normal distribution lies.
¿ = the standard deviation of the normal distribution
ERx estimates were not calculated for plant condition because those data are qualitative and therefore not conducive to statistical analysis. - Validity criteria fulfilled:
- not specified
- Conclusions:
- The effects of the test substance was evaluated on the seedling emergence of 3 species of non-target plants. A pre-emergence soil concentration of up to 100 mg/kg soil d.w. resulted in effects on all test species. The most sensitive case was Brassica napus which showed 21 day biomass NOEC and EC50 of 1 and 8.82 mg/kg.
- Executive summary:
Seeds of three species of non-target plants (A. sativa, B. napus and P. sativum) were planted in soils containing the test substance in concentrations of 1, 10 and 100 mg/kg soil d.w. as well as blank and solvent controls. Seedlings were measured for emergence, survival, height and biomass. No significant differences were measured between the solvent and blank controls. Treatment-related effects were observed in all species, with 21-day biomass being the most sensitive endpoint. The most sensitive species was Brassica napus which showed 21-day biomass NOEC and EC50of 1 and 8.82 mg/kg.
Referenceopen allclose all
Table 3: Effect Endpoints
Species | 21-Day Emergence (mg/kg d.w.) | 21-Day Survival (mg/kg d.w.) | 21-day Height (mg/kg d.w.) | 21-day Biomass (mg/kg d.w.) | ||||||||
LOEC | NOEC | EC50 | LOEC | NOEC | EC50 | LOEC | NOEC | EC50 | LOEC | NOEC | EC50 | |
Monocot: | ||||||||||||
Avena sativa (oat) | >100 | 100 | >100 | >100 | 100 | >100 | 100 | 10 | 44.6 | 10 | 1 | 13.9 |
Dicots: | ||||||||||||
Brassica napus (oilseed rape) | >100 | 100 | >100 | 100 | 10 | 55 | 10 | 1 | 10.1 | 10 | 1 | 8.82 |
Pisum sativum (pea) | >100 | 100 | >100 | >100 | 100 | >100 | 100 | 10 | 66.8 | 100 | 10 | 50.5 |
Detailed data on each species is provided in the study report
P.sativum seedlings showed no signs of phytotoxicity. In the 10 mg/kg d.w. group A. sativa showed slight necrosis which was accompanied by slight leaf curl in the 100 mg/kg d.w. treatment group. B. napus showed chlorosis and necrosis in the 10 mg/kg d.w. treatment group and total mortality in the 100 mg/kg d.w. treatment group.
Description of key information
EC50(biomass) = 13.9 mg/kg soil d.wt., NOEC(biomass)=1 mg/kg soil d.wt., Avena sativa, 21 days, OECD 208, Porch 2005
Key value for chemical safety assessment
- Short-term EC50 or LC50 for terrestrial plants:
- 8.82 mg/kg soil dw
- Long-term EC10, LC10 or NOEC for terrestrial plants:
- 1 mg/kg soil dw
Additional information
Seeds of three species of non-target plants (A. sativa, B. napus and P. sativum) were planted in soils containing the test substance in concentrations of 1, 10 and 100 mg/kg soil d.w. as well as blank and solvent controls. Seedlings were measured for emergence, survival, height and biomass. No significant differences were measured between the solvent and blank controls. Treatment-related effects were observed in all species, with 21-day biomass being the most sensitive endpoint. The most sensitive species (Avena sativa) showed 21-day biomass EC50=13.9 mg/kg soil d.wt. and NOEC=1 mg/kg soil d.wt.
The available study covers a sensitive stage in the life-cycle of a plant, and has thus been used as an estimate of chronic toxicity (Chapter R.7c, R.7.11.3.1). The study is considered to be reliable and adequate for risk assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
![ECHA](/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/echa_logo.png)