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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008-04-15 to 2008-04-24
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: without GLP
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
EU A6
Deviations:
no
GLP compliance:
no
Type of method:
flask method
Key result
Water solubility:
ca. 785.8 g/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
ca. 7.97

pretest:

29.022 g of test material in 20.04 mL deminaeralized water were not fully soluble.

 

Flask #1:

85 g test material in 50 mL demineralized water, difficult to stir. Assay result iodometric: 57.62 and 57.50, mean value 57.56 % w/w

 

Flask #2:

80 g test material in 50 mL demineralized water, easy to stir. Assay result iodometric: 57.45 and 57.45, mean value 57.45 % w/w

 

Flask #3:

73.7 g test material in 50 mL demineralized water, difficult to stir. Assay result iodometric: 57.62 and 57.51, mean value 57.565 % w/w

Rel. density of saturated solution at 20°C: 1.3654

Conclusions:
Interpretation of results (migrated information): very soluble (> 10'000 mg/L)
Water Solubility of the test material was determined to 785.8 +/- 0.11 g / L at 20°C
Executive summary:

with a solubility of 785.8 g/ L ths test material is higly water soluble

Description of key information

Solubility was measured according OECD /EU Guideline

Key value for chemical safety assessment

Water solubility:
785.8 g/L
at the temperature of:
20 °C

Additional information

Three measurement of the flask method were carried out with a deviation of less than 0.1% rel.