Registration Dossier
Registration Dossier
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EC number: 207-431-5 | CAS number: 470-82-6
Carcinogenicity
Administrative data
Description of key information
Key value for chemical safety assessment
Carcinogenicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Study duration:
- subchronic
- Species:
- mouse
Justification for classification or non-classification
Additional information
Groups of 52 male mice were given the test substance in toothpaste base by gavage for 80 weeks followed by an observation period between 16 and 24 weeks. No treatment-related effects on tumour incidence were observed.
Justification for selection of carcinogenicity via oral route endpoint:
Groups of 52 male mice were given the test substance in toothpaste base by gavage for 80 weeks followed by an observation period between 16 and 24 weeks. No treatment-related effects on tumour incidence were observed.
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