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EC number: 210-848-5 | CAS number: 624-48-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to fish
Administrative data
- Endpoint:
- long-term toxicity to fish, other
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Accepted calculation method
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
- Principles of method if other than guideline:
- ECOSAR v1.00
- GLP compliance:
- no
Test material
- Reference substance name:
- Dimethyl maleate
- EC Number:
- 210-848-5
- EC Name:
- Dimethyl maleate
- Cas Number:
- 624-48-6
- Molecular formula:
- C6H8O4
- IUPAC Name:
- dimethyl (Z)-but-2-enedioate
- Details on test material:
- - Name of test material (as cited in study report): dimethyl maleate
- Analytical purity: not applicable
SMILES : O=C(OC)C=CC(=O)OC
CHEM : 2-Butenedioic acid (Z)-, dimethyl ester
MOL FOR: C6 H8 O4
MOL WT : 144.13
Constituent 1
Test organisms
- Test organisms (species):
- other: Fish, not specified by ECOSAR
Study design
- Total exposure duration:
- 30 d
Results and discussion
Effect concentrations
- Duration:
- 30 d
- Dose descriptor:
- other: ChV
- Effect conc.:
- 0.694 mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- not specified
- Remarks on result:
- other: originally expressed as 0.694 ppm
Any other information on results incl. tables
SMILES :O=C(OC)C=CC(=O)OC
CHEM : 2-Butenedioic acid (Z)-,dimethylester
CAS Num: 000624-48-6
ChemID1:
ChemID2:
ChemID3:
MOL FOR: C6 H8 O4
MOL WT : 144.13
LogKow: 0.22 (Userentered)
MeltPt: -19.00degC
Wat Sol: 6.74E+004 mg/L (measured)
ECOSAR v1.00Class(es) Found
------------------------------
Acrylates
Predicted
ECOSAR Class Organism Duration EndPt mg/L (ppm)
=========================== ================== ======== ====== ==========
Acrylates : Fish 96-hr LC50 5.567
Acrylates :Daphnid 48-hr LC50 20.643
Acrylates : Green Algae 96-hr EC50 2.014
Acrylates : Fish 30-day ChV 0.694
Acrylates :Daphnid ChV 1.897 !
Acrylates : Green Algae ChV 0.720
Acrylates :Fish (SW) 96-hr LC50 2.308
Acrylates :MysidShrimp (SW) 96-hr LC50 4.375
Acrylates :Fish (SW) ChV 0.248 !
Acrylates :MysidShrimp (SW) ChV 0.749 !
=========================== ================== ======== ====== ==========
Neutral Organic SAR : Fish 96-hr LC50 3561.927
(Baseline Toxicity) :Daphnid 48-hr LC50 1657.429
: Green Algae 96-hr EC50 344.222
: Fish ChV 351.701
:Daphnid ChV 111.746
: Green Algae ChV 90.009
Note: * = asterisk designates: Chemical may not be soluble
enoughto measure this predicted effect.
Note: != exclamation designates: The toxicity value was determined from
apredicted SAR using established acute-to-chronic ratios and ECOSAR
regressiontechniques which are documented in the supporting Technical
Reference Manual.When possible, this toxicity value should be
consideredin a weight of evidence approach.
Acrylates:
---------
For Fish,DaphnidandMysidShrimp Acute Toxicity Values: If the logKow
of the chemical is greater than 5.0, or if the compound is solid and the LC50
exceedsthe water solubility by 10X, no effects at saturation are predicted
fortheseendpoints.
For Green Algae Acute Toxicity Values: If the logKowof the chemical is
greaterthan 6.4, or if the compound is solid and the EC50 exceeds the water
solubilityby 10X, no effects at saturation are predicted for these endpoints.
For All Chronic Toxicity Values: If the logKowof the chemical is greater
than 8.0, or if the compound is solid and theChVexceeds the water solubility
by 10X, no effects at saturation are predicted for these endpoints.
ECOSAR v1.00 SAR Limitations:
----------------------------
MaximumLogKow: 5.0 (LC50)
MaximumLogKow: 6.4 (EC50)
MaximumLogKow: 8.0 (ChV)
Maximum Mol Wt: 1000
Baseline Toxicity SAR Limitations:
---------------------------------
MaximumLogKow: 5.0 (Fish 96-hr LC50;DaphnidLC50)
MaximumLogKow: 6.4 (Green Algae EC50)
MaximumLogKow: 8.0 (ChV)
Maximum Mol Wt: 1000
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Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.