Registration Dossier
Registration Dossier
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EC number: 204-200-0 | CAS number: 117-61-3
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Authoritative data base
- Title:
- Danish QSAR study for CAS No.: 117-61-3
- Author:
- Danish EPA Model
- Year:
- 2 012
- Bibliographic source:
- QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database; DK-EPA
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: modelling database
- Principles of method if other than guideline:
- Skin irritation (Severe vs mild).Multicase model.
- GLP compliance:
- no
Test material
- Reference substance name:
- Benzidine-2,2’-disulphonic acid
- IUPAC Name:
- Benzidine-2,2’-disulphonic acid
- Reference substance name:
- Benzidine-2,2'-disulphonic acid
- EC Number:
- 204-200-0
- EC Name:
- Benzidine-2,2'-disulphonic acid
- Cas Number:
- 117-61-3
- Molecular formula:
- C12H12N2O6S2
- IUPAC Name:
- 4,4'-diamino-[1,1'-biphenyl]-2,2'-disulfonic acid
- Details on test material:
- - Name of test material: Benzidine-2,2’-disulphonic acid
- Molecular formula: C12H12N2O6S2
- Molecular weight: 344.369
- Substance type: organic
- Physical state: solid
Constituent 1
Constituent 2
Test animals
- Species:
- other: no data
- Strain:
- not specified
Test system
- Type of coverage:
- not specified
- Preparation of test site:
- not specified
- Vehicle:
- not specified
- Controls:
- not specified
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Reversibility:
- no data
- Remarks on result:
- other: Severe skin irritation: Negative
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Benzidine-2,2’-disulphonic acid was estimated to be non irritating to skin as per the prediction of the Danish EPA model.
- Executive summary:
Benzidine-2,2’-disulphonic acid was estimated to be non irritating to skin as per the prediction of the Danish EPA model.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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