Registration Dossier
Registration Dossier
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EC number: 203-607-0 | CAS number: 108-69-0
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Remarks:
- Study on behalf of competent authorities of Japan
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- not specified
- GLP compliance:
- yes
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- photometric method
- Key result
- Type:
- log Pow
- Partition coefficient:
- 1.83
- Temp.:
- 25 °C
- pH:
- 6.3
- Type:
- log Pow
- Partition coefficient:
- >= 1.66 - <= 2.09
- Temp.:
- 25 °C
- pH:
- 6.3
- Details on results:
- The results are rounded to three significant digits according to the method of JIS Z 8401-1961.
- Conclusions:
- The logPow was determined to be 1.83 at 25°C.
- Executive summary:
The partition coefficient of 3.5-Xylidine was evaluated in an GLP study according to OECD Guideline 107. The logPow was determined to be in the range of 1.66 - 2.09 and the mean measured logPow was 1.83 at 25°C.
Reference
Description of key information
OECD 107, logPow at 25°C was 1.83 +/- 0.18
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 1.83
- at the temperature of:
- 25 °C
Additional information
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