Registration Dossier
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EC number: 607-234-8 | CAS number: 234446-82-3
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
With high probability acutely not harmful to fish.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
To describe the short-term toxicity to fish a study with a representative mixture of ‘EDTA metal complexes with cobalt, copper, iron, manganese and zinc’ (CAS 234446-82-3) is available [Toxikon Corporation, on behalf of Ciba, 1999]. The study was conducted according to OECD guideline 203 under non-GLP conditions with Pimephales promelas as test species. Mortality of animals exposed to the test item ranged between 0 - 25%. The 96-hour LC50 value was incalculable because of the low mortality in the treatment concentrations. Therefore the NOEC and the LC50 is reported as >= 100 mg/L.
Further short-term toxicity studies with fish are available for the single components of the UVCB (FeEDTANa, CAS 15708-41-5; MnEDTANa2, CAS 15375-84-5; ZnEDTANa2, CAS 14025-21-9; CuEDTANa2 CAS 14025-15-1). These tests confirm the low toxicity of the EDTA metal complexes to fish. Thus the two main components of the UVCB (EDTA complexes with iron and manganese) caused no short-term effects on fish up to test concentration of 100 mg/L and 1000 mg/L, respectively.
The studies were conducted with the rainbow trout Onchorhynchus mykiss for FeNaEDTA (CAS 15708-41-5) [Eurofins-GAB, on behalf of Neudorff GmbH, 2007] and with zebra fish Danio rerio for MnEDTANa2 (CAS 15375-84-5) [Akzo Nobel, 2007]. Both studies followed the test procedure described in OECD guideline 203, under GLP conditions and with analytical monitoring of the test item concentration.
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