Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-861-7 | CAS number: 88-85-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
In a ready biodegradability study (OECD 301B) only 24% biodegradation to carbon dioxide was observed after 29 days. Based on this data, Dinoseb is defined as not readily biodegradable.
Photo degradation data generated by Saxena (1987) and Blair (1986) show that Dinoseb can be expected to photo-degrade in water. At low concentrations, (5-10mg/L) a half-life of 12-18 days was determined. Hydrolysis of the substance will not be significant.
Photo degradation studies in soil (Hazelton, 1986), (Saxena, 1989), showed the half-life of Dinoseb to drastically decrease when exposed to natural sunlight, suggesting that photolytic degradation from soil surface may be an important degradation pathway. The half-life determined by the soil photolysis studies ranged between 0.6 and 6.2 days.
Dinoseb was used for many years as an herbicide at very high rates. The Food and Agriculture Organisation (FAO) reports thatDinoseb is of low persistence, regardless of the form (phenol or salt), reporting field half-lives for both types of Dinoseb in the range 5 to 31 days.
Stevenset al. (1990) [Appl Environ Microbiol.1990 January; 56(1): 133-139] examined the ability of native microorganisms in various Idaho soils to degrade Dinoseb, in addition to physical and chemical soil characteristics which might affect the biodegradation process. Biodegradation rates were higher in silt-loam soils than in loamy-sand soils. Bacterial numbers were the best predictors of biodegradation rates, accounting for 53% of the variability between soils. Soil nitrate-N inhibited Dinoseb biodegradation and accounted for 39% of the variability. Sorption of Dinoseb to soil surfaces also appeared to influence biodegradation rates. It was shown that biodegradation of Dinoseb can occur in soils and is not dependent on long term acclimation to the substance.
Extensive metabolism and mineralisation of14C-phenyl Dinoseb occurred by isolated soil microorganism cultures (Hammill and Crawford 1996). Rapid degradation of Dinoseb was observed via co-metabolism in the presence of a fermentable carbon source. The formed anaerobic degradation products were incubated with aerobic soil bacteria and shown to further mineralise to carbon dioxide.
Based on the available data, Dinoseb can be considered to be ‘inherently biodegradable – not fulfilling criteria’. Extensive metabolism and mineralisation of Dinoseb by isolated soil microorganism cultures has been observed, therefore it is likely that Dinoseb will completely be degraded in an STP, particularly as the concentration would be expected to be low. Exposure of marine waters and sediments are unlikely, however it is considered that the half-lives for these compartments would not differ significantly from those demonstrated in freshwater systems.
It is therefore concluded that Dinoseb does not satisfy the persistence criteria (not P or vP).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.